IL9R_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IL9R_HUMAN
• UniProt AC: Q01113
• Protein Name: Interleukin-9 receptor
• Gene Name: IL9R
• Organism: Homo sapiens (Human).
• Sequence Length: 521
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Secreted.
• Protein Description: This is a receptor for interleukin-9..
• Protein Sequence: MGLGRCIWEGWTLESEALRRDMGTWLLACICICTCVCLGVSVTGEGQGPRSRTFTCLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQSSGPIPALACGLSCDHQGLETQQGVAWVLAGHCQRPGLHEDLQGMLLPSVLSKARSWTF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19 (in isoform 3)	Ubiquitination	-	39.33	-
94	Ubiquitination	QAPGGTHKCILRGSE CCCCCEEEEEECCCC	23.86	-
117	N-linked_Glycosylation	AVLVPSDNFTITFHH EEEECCCCEEEEEEE	40.05	UniProtKB CARBOHYD
156	N-linked_Glycosylation	PPSDLQSNISSGHCI CCHHHHHHCCCCEEE	25.79	UniProtKB CARBOHYD
187	Ubiquitination	SYELAFKKQEEAWEQ HHHHHHHHHHHHHHH	57.39	-
230	Phosphorylation	RLRVQMATLEDDVVE HHHHEEEECCCCCEE	25.90	-
407	Phosphorylation	WRVQTLAYLPQEDWA EEEEEEEECCHHHCC	23.25	8756628
514	Phosphorylation	MLLPSVLSKARSWTF CCHHHHHHHHHCCCC	23.32	24719451
518	Phosphorylation	SVLSKARSWTF---- HHHHHHHCCCC----	35.01	10642536
520	Phosphorylation	LSKARSWTF------ HHHHHCCCC------	22.25	10642536

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IL9R_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IL9R_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IL9R_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KAT5_HUMAN	KAT5	physical	10486269
LSR_HUMAN	LSR	physical	26186194
CCPG1_HUMAN	CCPG1	physical	26186194
SARAF_HUMAN	SARAF	physical	26186194
RETST_HUMAN	RETSAT	physical	26186194
DHRS7_HUMAN	DHRS7	physical	26186194
IDD_HUMAN	DGCR2	physical	26186194
TTC17_HUMAN	TTC17	physical	26186194
NETO2_HUMAN	NETO2	physical	26186194
TM39A_HUMAN	TMEM39A	physical	26186194
ABCBA_HUMAN	ABCB10	physical	26186194
POMT1_HUMAN	POMT1	physical	26186194
EDA_HUMAN	EDA	physical	26186194
PDE3B_HUMAN	PDE3B	physical	26186194
TM2D3_HUMAN	TM2D3	physical	26186194
ZDH18_HUMAN	ZDHHC18	physical	26186194
TM205_HUMAN	TMEM205	physical	26186194
UBE4A_HUMAN	UBE4A	physical	26186194
EDA_HUMAN	EDA	physical	28514442
RETST_HUMAN	RETSAT	physical	28514442
ZDH18_HUMAN	ZDHHC18	physical	28514442
LSR_HUMAN	LSR	physical	28514442
SARAF_HUMAN	SARAF	physical	28514442
NETO2_HUMAN	NETO2	physical	28514442
TMX4_HUMAN	TMX4	physical	28514442
TM39A_HUMAN	TMEM39A	physical	28514442
TM2D3_HUMAN	TM2D3	physical	28514442
CCPG1_HUMAN	CCPG1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.