| UniProt ID | FHL5_HUMAN | |
|---|---|---|
| UniProt AC | Q5TD97 | |
| Protein Name | Four and a half LIM domains protein 5 | |
| Gene Name | FHL5 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 284 | |
| Subcellular Localization | Nucleus . Nuclei of round and elongated spermatids. | |
| Protein Description | May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.. | |
| Protein Sequence | MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MTTAHFYCQYCTAS -CCCHHHHHHHHHHH | 2.93 | 29759185 | |
| 12 | Phosphorylation | HFYCQYCTASLLGKK HHHHHHHHHHHCCCE | 17.85 | 26503514 | |
| 18 | Ubiquitination | CTASLLGKKYVLKDD HHHHHCCCEEEECCC | 40.68 | - | |
| 20 | Phosphorylation | ASLLGKKYVLKDDSP HHHCCCEEEECCCCC | 17.94 | 29759185 | |
| 50 | Phosphorylation | ECKKPIESDSKDLCY HCCCCCCCCCCCCCC | 48.15 | 29083192 | |
| 52 | Phosphorylation | KKPIESDSKDLCYKD CCCCCCCCCCCCCCC | 37.03 | 29083192 | |
| 57 | Phosphorylation | SDSKDLCYKDRHWHE CCCCCCCCCCCCCCC | 24.18 | 29083192 | |
| 114 | Methylation | RTIMPGSRKMEFKGN CCCCCCCCCEEEECC | 48.53 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FHL5_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FHL5_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FHL5_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FHL5_HUMAN | FHL5 | physical | 11046156 | |
| DNAL4_HUMAN | DNAL4 | physical | 16189514 | |
| CREM_HUMAN | CREM | physical | 11046156 | |
| CREB1_HUMAN | CREB1 | physical | 11046156 | |
| CREM_HUMAN | CREM | physical | 10086359 | |
| ZN446_HUMAN | ZNF446 | physical | 20211142 | |
| SCNM1_HUMAN | SCNM1 | physical | 26186194 | |
| ZNF24_HUMAN | ZNF24 | physical | 26186194 | |
| TAXB1_HUMAN | TAX1BP1 | physical | 26186194 | |
| ZMYM6_HUMAN | ZMYM6 | physical | 26186194 | |
| ZMYM1_HUMAN | ZMYM1 | physical | 26186194 | |
| PDLI7_HUMAN | PDLIM7 | physical | 26186194 | |
| CEP76_HUMAN | CEP76 | physical | 26186194 | |
| KAISO_HUMAN | ZBTB33 | physical | 26186194 | |
| CTU1_HUMAN | CTU1 | physical | 26186194 | |
| ZN131_HUMAN | ZNF131 | physical | 26186194 | |
| CEP76_HUMAN | CEP76 | physical | 28514442 | |
| TAXB1_HUMAN | TAX1BP1 | physical | 28514442 | |
| ZN131_HUMAN | ZNF131 | physical | 28514442 | |
| ZMYM1_HUMAN | ZMYM1 | physical | 28514442 | |
| SCNM1_HUMAN | SCNM1 | physical | 28514442 | |
| ZMYM6_HUMAN | ZMYM6 | physical | 28514442 | |
| PDLI7_HUMAN | PDLIM7 | physical | 28514442 | |
| CTU1_HUMAN | CTU1 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
