DNAL4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DNAL4_HUMAN
• UniProt AC: O96015
• Protein Name: Dynein light chain 4, axonemal
• Gene Name: DNAL4
• Organism: Homo sapiens (Human).
• Sequence Length: 105
• Subcellular Localization: Cytoplasm, cytoskeleton, cilium axoneme.
• Protein Description: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity)..
• Protein Sequence: MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	PEEMRVETMELCVTA CHHHHHHHHHHHHHH	17.06	26074081
55	Ubiquitination	NNNESAAKMIKETMD CCCHHHHHHHHHHHH	40.66	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DNAL4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DNAL4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DNAL4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DYL2_HUMAN	DYNLL2	physical	16189514
SCTR_HUMAN	SCTR	physical	21988832
GPBP1_HUMAN	GPBP1	physical	21988832
TRI54_HUMAN	TRIM54	physical	25416956
DYL2_HUMAN	DYNLL2	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956
FHL5_HUMAN	FHL5	physical	21516116

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.