FAM9A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FAM9A_HUMAN
• UniProt AC: Q8IZU1
• Protein Name: Protein FAM9A
• Gene Name: FAM9A
• Organism: Homo sapiens (Human).
• Sequence Length: 332
• Subcellular Localization: Nucleus, nucleolus .
• Protein Sequence: MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSEESELDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	AQLEAQVTAAQGATK HHHHHHHHHHCCCCC	12.28	24275569
28	Phosphorylation	VTAAQGATKEGSGIA HHHHCCCCCCCCCCC	36.13	22985185
32	Phosphorylation	QGATKEGSGIASNFP CCCCCCCCCCCCCCC	28.28	24275569
36	Phosphorylation	KEGSGIASNFPGQPT CCCCCCCCCCCCCCC	36.76	24275569

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FAM9A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FAM9A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FAM9A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	23455924
ANM1_HUMAN	PRMT1	physical	23455924
JMJD6_HUMAN	JMJD6	physical	23455924
KMT5A_HUMAN	SETD8	physical	23455924
ACD11_HUMAN	ACAD11	physical	26186194
NOLC1_HUMAN	NOLC1	physical	26186194
GOPC_HUMAN	GOPC	physical	26186194
CAVN1_HUMAN	PTRF	physical	26186194
AF9_HUMAN	MLLT3	physical	26186194
PININ_HUMAN	PNN	physical	26186194
NAF1_HUMAN	NAF1	physical	26186194
RNPS1_HUMAN	RNPS1	physical	26186194
SRRM2_HUMAN	SRRM2	physical	26186194
AP3B1_HUMAN	AP3B1	physical	26186194
AP3M1_HUMAN	AP3M1	physical	26186194
CWC22_HUMAN	CWC22	physical	26186194
JMJD6_HUMAN	JMJD6	physical	26186194
NP1L3_HUMAN	NAP1L3	physical	26186194
AFF4_HUMAN	AFF4	physical	26186194
PXDC2_HUMAN	PLXDC2	physical	26186194
GOPC_HUMAN	GOPC	physical	28514442
NP1L3_HUMAN	NAP1L3	physical	28514442
NAF1_HUMAN	NAF1	physical	28514442
CAVN1_HUMAN	PTRF	physical	28514442
CWC22_HUMAN	CWC22	physical	28514442
AF9_HUMAN	MLLT3	physical	28514442
AFF4_HUMAN	AFF4	physical	28514442
AP3B1_HUMAN	AP3B1	physical	28514442
SRRM2_HUMAN	SRRM2	physical	28514442
NOLC1_HUMAN	NOLC1	physical	28514442
ACD11_HUMAN	ACAD11	physical	28514442
PININ_HUMAN	PNN	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.