| UniProt ID | ETFR1_HUMAN | |
|---|---|---|
| UniProt AC | Q6IPR1 | |
| Protein Name | Electron transfer flavoprotein regulatory factor 1 {ECO:0000312|HGNC:HGNC:27052} | |
| Gene Name | ETFRF1 {ECO:0000312|HGNC:HGNC:27052} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 90 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB).. | |
| Protein Sequence | MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGEFVMKELEALYFLRKYRAMKQRYYSDTNKTN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 44 | Ubiquitination | KNIFLKNKDVKNPEK HHHHHCCCCCCCHHH | - | ||
| 51 | Ubiquitination | KDVKNPEKIKELIAQ CCCCCHHHHHHHHHC | - | ||
| 70 | Phosphorylation | MKELEALYFLRKYRA HHHHHHHHHHHHHHH | - | ||
| 82 | Phosphorylation | YRAMKQRYYSDTNKT HHHHHHHHHCCCCCC | 30622161 | ||
| 83 | Phosphorylation | RAMKQRYYSDTNKTN HHHHHHHHCCCCCCC | 30622161 | ||
| 84 | Phosphorylation | AMKQRYYSDTNKTN- HHHHHHHCCCCCCC- | 30622161 | ||
| 86 | Phosphorylation | KQRYYSDTNKTN--- HHHHHCCCCCCC--- | 30622161 | ||
| 89 | Phosphorylation | YYSDTNKTN------ HHCCCCCCC------ | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ETFR1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ETFR1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ETFR1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ETFA_HUMAN | ETFA | physical | 27499296 | |
| ETFB_HUMAN | ETFB | physical | 27499296 | |
| ETFR1_HUMAN | LYRM5 | physical | 27499296 | |
| NT5D2_HUMAN | NT5DC2 | physical | 27499296 | |
| RM46_HUMAN | MRPL46 | physical | 27499296 | |
| CYC_HUMAN | CYCS | physical | 27499296 | |
| ACPM_HUMAN | NDUFAB1 | physical | 27499296 | |
| ECH1_HUMAN | ECH1 | physical | 27499296 | |
| CHCH2_HUMAN | CHCHD2 | physical | 27499296 | |
| RCC1L_HUMAN | WBSCR16 | physical | 27499296 | |
| C1QBP_HUMAN | C1QBP | physical | 27499296 | |
| ETFA_HUMAN | ETFA | physical | 28514442 | |
| ETFB_HUMAN | ETFB | physical | 28514442 | |
| ACPM_HUMAN | NDUFAB1 | physical | 28514442 | |
| RM46_HUMAN | MRPL46 | physical | 28514442 | |
| NAKD2_HUMAN | NADK2 | physical | 28514442 | |
| SPT20_HUMAN | SPATA20 | physical | 28514442 | |
| NT5D2_HUMAN | NT5DC2 | physical | 28514442 | |
| CCZ1B_HUMAN | CCZ1 | physical | 28514442 | |
| CCZ1_HUMAN | CCZ1 | physical | 28514442 | |
| KLH22_HUMAN | KLHL22 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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