| UniProt ID | CYP59_ARATH | |
|---|---|---|
| UniProt AC | Q6Q151 | |
| Protein Name | Peptidyl-prolyl cis-trans isomerase CYP59 | |
| Gene Name | CYP59 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 506 | |
| Subcellular Localization | Nucleus . Shows a punctuate localization pattern distinct from the nuclear speckles. | |
| Protein Description | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Influences somehow regulation of RNA pol II (CTD) phosphorylation. Binds RNA with preferences for GC-rich sequences. Probably involved in activities connecting transcription and pre-mRNA processing. Involved in brassinostroid response.. | |
| Protein Sequence | MSVLIVTSLGDIVIDLHSDKCPLTCKNFLKLCKIKYYNGCLFHTVQKDFTAQTGDPTGTGAGGDSIYKFLYGEQARFYKDEIHLDLKHSKTGTVAMASGGENLNASQFYFTLRDDLDYLDGKHTVFGQIAEGFDTLTRINEAYVDPKNRPYKNIRIKHTHILDDPFDDPPQLAEMMPDASPEGKPKEEVKDDVRLEDDWVPMDEELGAQELEEVIREKAAHSSAVVLESIGDIPEAEVKPPDNVLFVCKLNPVTEDEDLHTIFSRFGTVVSADVIRDFKTGDSLCYAFIEFENKESCEQAYFKMDNALIDDRRIHVDFSQSVSKLWSQFRQKDSQKGKGNGCFKCGSTDHIAKDCVGGPSSKFIVKDQNRQHGGGEGYEMVFEGDVHETPKHNSHERERSEKIQRRSPHGNGEGKRQHRDERDDGRRQHDREDARELERKHRERKERESREDEDRRRRRRREESRDKESRRERDEDDHRSHRDYKERRRERDDRHGREARHERRDR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 180 | Phosphorylation | AEMMPDASPEGKPKE HHHCCCCCCCCCCHH | 30291188 | ||
| 362 | Acetylation | CVGGPSSKFIVKDQN CCCCCCCEEEEEECC | 21311031 | ||
| 407 | Phosphorylation | SEKIQRRSPHGNGEG HHHHHHHCCCCCCCC | 25561503 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CYP59_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CYP59_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CYP59_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SRC28_ARATH | SCL28 | physical | 16497658 | |
| SRC30_ARATH | SCL30 | physical | 16497658 | |
| SL30A_ARATH | SCL30A | physical | 16497658 | |
| SRC33_ARATH | SR33 | physical | 16497658 | |
| SR34_ARATH | SR1 | physical | 16497658 | |
| RSZ21_ARATH | RSZP21 | physical | 16497658 | |
| RSZ33_ARATH | RSZ33 | physical | 16497658 | |
| SC35_ARATH | SC35 | physical | 16497658 | |
| SR30_ARATH | ATSRP30 | physical | 16497658 | |
| SRS31_ARATH | RSP31 | physical | 16497658 | |
| RS40_ARATH | RSP35 | physical | 16497658 | |
| NRPB1_ARATH | NRPB1 | physical | 16497658 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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