SRC30_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SRC30_ARATH
• UniProt AC: Q8L3X8
• Protein Name: Serine/arginine-rich SC35-like splicing factor SCL30
• Gene Name: SCL30
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 262
• Subcellular Localization: Nucleus speckle .
• Protein Description: Involved in intron recognition and spliceosome assembly (Probable). Probably active at the 5' splice sites..
• Protein Sequence: MRRYSPPYYSPPRRGYGGRGRSPPPPPPRRGYGGGGGGGGRRGSSHGSLLVRNIPLDCRPEELREPFERFGPVRDVYIPRDYYSGQPRGFAFVEFVDAYDAGEAQRSMNRRSFAGREITVVVASESRKRPEEMRVKTRTRSREPSGSRDRSHGRSRSRSISRSRSPRRPSDSRSRYRSRSYSPAPRRRGGPPRGEEDENYSRRSYSPGYEGAAAAAPDRDRNGDNEIREKPGYEAEDRRRGGRAVSRSPSGSRSRSVEVSPR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MRRYSPPYYSP ----CCCCCCCCCCC		23776212
5	Phosphorylation	---MRRYSPPYYSPP ---CCCCCCCCCCCC		30291188
8	Phosphorylation	MRRYSPPYYSPPRRG CCCCCCCCCCCCCCC		24601666
9	Phosphorylation	RRYSPPYYSPPRRGY CCCCCCCCCCCCCCC		23776212
10	Phosphorylation	RYSPPYYSPPRRGYG CCCCCCCCCCCCCCC		30291188
22	Phosphorylation	GYGGRGRSPPPPPPR CCCCCCCCCCCCCCC		30291188
44	Phosphorylation	GGGGRRGSSHGSLLV CCCCCCCCCCCCEEE		19880383
48	Phosphorylation	RRGSSHGSLLVRNIP CCCCCCCCEEEECCC		29797451
176	Phosphorylation	PSDSRSRYRSRSYSP CCCCHHHHHHCCCCC		23776212
178	Phosphorylation	DSRSRYRSRSYSPAP CCHHHHHHCCCCCCC		23776212
180	Phosphorylation	RSRYRSRSYSPAPRR HHHHHHCCCCCCCCC		23776212
181	Phosphorylation	SRYRSRSYSPAPRRR HHHHHCCCCCCCCCC		23776212
182	Phosphorylation	RYRSRSYSPAPRRRG HHHHCCCCCCCCCCC		23776212
200	Phosphorylation	RGEEDENYSRRSYSP CCCCCCCCCCCCCCC		23111157
201	Phosphorylation	GEEDENYSRRSYSPG CCCCCCCCCCCCCCC		30407730
204	Phosphorylation	DENYSRRSYSPGYEG CCCCCCCCCCCCCCC		30291188
205	Phosphorylation	ENYSRRSYSPGYEGA CCCCCCCCCCCCCCC		24601666
206	Phosphorylation	NYSRRSYSPGYEGAA CCCCCCCCCCCCCCH		30291188
209	Phosphorylation	RRSYSPGYEGAAAAA CCCCCCCCCCCHHHC		19880383
246	Phosphorylation	RRGGRAVSRSPSGSR HCCCCEECCCCCCCC		29654922
248	Phosphorylation	GGRAVSRSPSGSRSR CCCEECCCCCCCCCC		25561503
252	Phosphorylation	VSRSPSGSRSRSVEV ECCCCCCCCCCCEEE		29654922
254	Phosphorylation	RSPSGSRSRSVEVSP CCCCCCCCCCEEECC		23776212
256	Phosphorylation	PSGSRSRSVEVSPR- CCCCCCCCEEECCC-		19880383
260	Phosphorylation	RSRSVEVSPR----- CCCCEEECCC-----		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SRC30_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SRC30_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SRC30_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RSZ21_ARATH	RSZP21	physical	18674533
SR30_ARATH	ATSRP30	physical	18674533
SR34_ARATH	SR1	physical	18674533
SRC28_ARATH	SCL28	physical	18674533
SRC30_ARATH	SCL30	physical	18674533
SL30A_ARATH	SCL30A	physical	18674533
RSZ33_ARATH	RSZ33	physical	12176998
RZ1C_ARATH	AT5G04280	physical	21798944
AFC3_ARATH	AME3	physical	21798944
U2AFB_ARATH	U2AF35B	physical	21798944
SRC30_ARATH	SCL30	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.