SL30A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SL30A_ARATH
• UniProt AC: Q9LHP2
• Protein Name: Serine/arginine-rich SC35-like splicing factor SCL30A
• Gene Name: SCL30A
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 262
• Subcellular Localization: Nucleus speckle .
• Protein Description: Involved in intron recognition and spliceosome assembly. Binds probably to multiple 5'-GAAG-3' repeats found in its third intron, suggesting autoregulation of alternative splicing. [PubMed: 22913769 May be necessary for accurate splicing of the 3' region of introns.]
• Protein Sequence: MRGRSYTPSPPRGYGRRGRSPSPRGRFGGSRDSDLPTSLLVRNLRHDCRQEDLRRPFEQFGPVKDIYLPRDYYTGDPRGFGFIQFMDPADAAEAKHQMDGYLLLGRELTVVFAEENRKKPTEMRTRDRGGRSNRFQDRRRSPPRYSRSPPPRRGRRSRSRSRGYNSPPAKRHQSRSVSPQDRRYEKERSYSRSPPHNGSRVRSGSPGRVKSHSRSPRRSVSPRKNRSYTPEQARSQSPVPRQSRSPTPVPRGAQNGDRSPSQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MRGRSYTPSPPR ---CCCCCCCCCCCC		23776212
6	Phosphorylation	--MRGRSYTPSPPRG --CCCCCCCCCCCCC		23776212
7	Phosphorylation	-MRGRSYTPSPPRGY -CCCCCCCCCCCCCC		23776212
9	Phosphorylation	RGRSYTPSPPRGYGR CCCCCCCCCCCCCCC		23776212
14	Phosphorylation	TPSPPRGYGRRGRSP CCCCCCCCCCCCCCC		23776212
20	Phosphorylation	GYGRRGRSPSPRGRF CCCCCCCCCCCCCCC		23776212
22	Phosphorylation	GRRGRSPSPRGRFGG CCCCCCCCCCCCCCC		23776212
30	Phosphorylation	PRGRFGGSRDSDLPT CCCCCCCCCCCCCCH		30589143
146	Phosphorylation	RRSPPRYSRSPPPRR CCCCCCCCCCCCCCC		29654922
148	Phosphorylation	SPPRYSRSPPPRRGR CCCCCCCCCCCCCCC		25561503
161	Phosphorylation	GRRSRSRSRGYNSPP CCCCCCHHCCCCCCC		30407730
164	Phosphorylation	SRSRSRGYNSPPAKR CCCHHCCCCCCCHHH		23776212
166	Phosphorylation	SRSRGYNSPPAKRHQ CHHCCCCCCCHHHHC		23776212
174	Phosphorylation	PPAKRHQSRSVSPQD CCHHHHCCCCCCHHH		23111157
176	Phosphorylation	AKRHQSRSVSPQDRR HHHHCCCCCCHHHHH		23111157
178	Phosphorylation	RHQSRSVSPQDRRYE HHCCCCCCHHHHHHH		23111157
189	Phosphorylation	RRYEKERSYSRSPPH HHHHHHHHCCCCCCC		29654922
190	Phosphorylation	RYEKERSYSRSPPHN HHHHHHHCCCCCCCC		25561503
191	Phosphorylation	YEKERSYSRSPPHNG HHHHHHCCCCCCCCC		25561503
193	Phosphorylation	KERSYSRSPPHNGSR HHHHCCCCCCCCCCC		29654922
199	Phosphorylation	RSPPHNGSRVRSGSP CCCCCCCCCCCCCCC		25561503
203	Phosphorylation	HNGSRVRSGSPGRVK CCCCCCCCCCCCCCC		25561503
205	Phosphorylation	GSRVRSGSPGRVKSH CCCCCCCCCCCCCCC		25561503
227	Phosphorylation	VSPRKNRSYTPEQAR CCCCCCCCCCHHHHH		23776212
228	Phosphorylation	SPRKNRSYTPEQARS CCCCCCCCCHHHHHC		23776212
229	Phosphorylation	PRKNRSYTPEQARSQ CCCCCCCCHHHHHCC		23776212
235	Phosphorylation	YTPEQARSQSPVPRQ CCHHHHHCCCCCCCC		23776212
237	Phosphorylation	PEQARSQSPVPRQSR HHHHHCCCCCCCCCC		23776212
243	Phosphorylation	QSPVPRQSRSPTPVP CCCCCCCCCCCCCCC		19376835
245	Phosphorylation	PVPRQSRSPTPVPRG CCCCCCCCCCCCCCC		19376835
247	Phosphorylation	PRQSRSPTPVPRGAQ CCCCCCCCCCCCCCC		19880383
259	Phosphorylation	GAQNGDRSPSQ---- CCCCCCCCCCC----		25561503
261	Phosphorylation	QNGDRSPSQ------ CCCCCCCCC------		29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SL30A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SL30A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SL30A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RSZ21_ARATH	RSZP21	physical	18674533
SR30_ARATH	ATSRP30	physical	18674533
SR34_ARATH	SR1	physical	18674533
SRC28_ARATH	SCL28	physical	18674533
SRC30_ARATH	SCL30	physical	18674533
SL30A_ARATH	SCL30A	physical	18674533
RSZ33_ARATH	RSZ33	physical	12176998

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.