SRC28_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SRC28_ARATH
• UniProt AC: Q1PDV2
• Protein Name: Serine/arginine-rich SC35-like splicing factor SCL28
• Gene Name: SCL28
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 236
• Subcellular Localization: Nucleus speckle .
• Protein Description: Involved in intron recognition and spliceosome assembly (Probable). Probably active at the 5' splice sites..
• Protein Sequence: MARARSRSRSYSPRPRDRSPPRERKGYDDNRLRERPSSRDHESSGPSGLLIRNLPLDARPNDLRDSFERFGPLKDIYLPRNYYTGEPRGFGFVKYRYAEDAAEAMKRMNHKVIGGREIAIVFAEENRKTPQEMRTTNGTSGRHGDYKRTSHRSPRRRYRSHSRSRSPPRRESRHSKVREDDLYSPRRRSRSISRSPLPRNEREYKSRNCRSPREERVLTPIRSRCLSRSRSRSLSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	RARSRSRSYSPRPRD CCCCCCCCCCCCCCC		28011693
11	Phosphorylation	ARSRSRSYSPRPRDR CCCCCCCCCCCCCCC		28011693
12	Phosphorylation	RSRSRSYSPRPRDRS CCCCCCCCCCCCCCC		28011693
19	Phosphorylation	SPRPRDRSPPRERKG CCCCCCCCCCCCCCC		27531888
164	Phosphorylation	RYRSHSRSRSPPRRE HHHCCCCCCCCCCHH		23776212
166	Phosphorylation	RSHSRSRSPPRRESR HCCCCCCCCCCHHHH		23776212
183	Phosphorylation	KVREDDLYSPRRRSR CCCHHHCCCCHHHCC		25561503
184	Phosphorylation	VREDDLYSPRRRSRS CCHHHCCCCHHHCCC		30291188
191	Phosphorylation	SPRRRSRSISRSPLP CCHHHCCCCCCCCCC		25561503
193	Phosphorylation	RRRSRSISRSPLPRN HHHCCCCCCCCCCCC		25561503
195	Phosphorylation	RSRSISRSPLPRNER HCCCCCCCCCCCCHH		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SRC28_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SRC28_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SRC28_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RSZ21_ARATH	RSZP21	physical	18674533
SR34_ARATH	SR1	physical	18674533
SRC28_ARATH	SCL28	physical	18674533
SRC30_ARATH	SCL30	physical	18674533
SL30A_ARATH	SCL30A	physical	18674533
SR30_ARATH	ATSRP30	physical	18674533
RSZ33_ARATH	RSZ33	physical	12176998

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.