SR30_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SR30_ARATH
• UniProt AC: Q9XFR5
• Protein Name: Serine/arginine-rich splicing factor SR30
• Gene Name: SR30
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 268
• Subcellular Localization: Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Inhibition of phosphorylation causes suppression of nuclear localization.
• Protein Description: Regulatory splicing factor that modulates alternative splicing and gene expression in specific cell types. Autoregulates its own expression. Probably involved in intron recognition and spliceosome assembly..
• Protein Sequence: MSSRWNRTIYVGNLPGDIRKCEVEDLFYKYGPIVDIDLKIPPRPPGYAFVEFEDPRDADDAIYGRDGYDFDGCRLRVEIAHGGRRFSPSVDRYSSSYSASRAPSRRSDYRVLVTGLPPSASWQDLKDHMRKAGDVCFSEVFPDRKGMSGVVDYSNYDDMKYAIRKLDATEFRNAFSSAYIRVREYESRSVSRSPDDSKSYRSRSRSRGPSCSYSSKSRSVSPARSISPRSRPLSRSRSLYSSVSRSQSRSKSRSRSRSNSPVSPVISG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
87	Phosphorylation	AHGGRRFSPSVDRYS EECCCCCCCCHHHCC		23111157
89	Phosphorylation	GGRRFSPSVDRYSSS CCCCCCCCHHHCCCC		29654922
189	Phosphorylation	VREYESRSVSRSPDD EEEECCCCCCCCCCC		25561503
191	Phosphorylation	EYESRSVSRSPDDSK EECCCCCCCCCCCCH		25561503
193	Phosphorylation	ESRSVSRSPDDSKSY CCCCCCCCCCCCHHH		25561503
197	Phosphorylation	VSRSPDDSKSYRSRS CCCCCCCCHHHHHCC		25561503
210	Phosphorylation	RSRSRGPSCSYSSKS CCCCCCCCCCCCCCC		-
212	Phosphorylation	RSRGPSCSYSSKSRS CCCCCCCCCCCCCCC		-
214	Phosphorylation	RGPSCSYSSKSRSVS CCCCCCCCCCCCCCC		-
219	Phosphorylation	SYSSKSRSVSPARSI CCCCCCCCCCCCCCC		-
221	Phosphorylation	SSKSRSVSPARSISP CCCCCCCCCCCCCCC		-
227	Phosphorylation	VSPARSISPRSRPLS CCCCCCCCCCCCCCC		19880383
230	Phosphorylation	ARSISPRSRPLSRSR CCCCCCCCCCCCCCH		19880383
236	Phosphorylation	RSRPLSRSRSLYSSV CCCCCCCCHHHHHHH		-
246	Phosphorylation	LYSSVSRSQSRSKSR HHHHHHHHHHHCCCC		-
256	Phosphorylation	RSKSRSRSRSNSPVS HCCCCCCCCCCCCCC		-
260	Phosphorylation	RSRSRSNSPVSPVIS CCCCCCCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SR30_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SR30_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SR30_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RZ1C_ARATH	AT5G04280	physical	21798944
SRS41_ARATH	ATRSP41	physical	21798944
RU17_ARATH	U1-70K	physical	21798944
RZ1B_ARATH	AT1G60650	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.