| UniProt ID | RU17_ARATH | |
|---|---|---|
| UniProt AC | Q42404 | |
| Protein Name | U1 small nuclear ribonucleoprotein 70 kDa | |
| Gene Name | RNU1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 427 | |
| Subcellular Localization | Nucleus speckle . Nucleus, nucleoplasm . The exchange between speckles and nucleoplasm is sensitive to ongoing transcription and phosphorylation. | |
| Protein Description | Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA.. | |
| Protein Sequence | MGDSGDPFLRNPNAAVQARAKVQNRANVLQLKLMGQSHPTGLTNNLLKLFEPRPPLEYKPPPEKRKCPPYTGMAQFVSNFAEPGDPEYAPPKPEVELPSQKRERIHKLRLEKGVEKAAEDLKKYDPNNDPNATGDPYKTLFVSRLNYESSESKIKREFESYGPIKRVHLVTDQLTNKPKGYAFIEYMHTRDMKAAYKQADGQKIDGRRVLVDVERGRTVPNWRPRRLGGGLGTSRVGGGEEIVGEQQPQGRTSQSEEPSRPREEREKSREKGKERERSRELSHEQPRERSRDRPREDKHHRDRDQGGRDRDRDSRRDRDRTRDRGDRDRRDRDRGRDRTSRDHDRDRSRKKERDYEGGEYEHEGGGRSRERDAEYRGEPEETRGYYEDDQGDTDRYSHRYDKMEEDDFRYEREYKRSKRSESREYVR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 252 | Phosphorylation | EQQPQGRTSQSEEPS CCCCCCCCCCCCCCC | 37.63 | 23776212 | |
| 253 | Phosphorylation | QQPQGRTSQSEEPSR CCCCCCCCCCCCCCC | 30.28 | 23776212 | |
| 255 | Phosphorylation | PQGRTSQSEEPSRPR CCCCCCCCCCCCCHH | 43.63 | 23776212 | |
| 259 | Phosphorylation | TSQSEEPSRPREERE CCCCCCCCCHHHHHH | 59.19 | 19376835 | |
| 278 | Phosphorylation | KGKERERSRELSHEQ HHHHHHHHHHHCCCC | 25.92 | 30291188 | |
| 282 | Phosphorylation | RERSRELSHEQPRER HHHHHHHCCCCCCHH | 21.89 | 30291188 | |
| 368 | Phosphorylation | EHEGGGRSRERDAEY CCCCCCCCCCCHHHH | 41.59 | 25368622 | |
| 420 | Phosphorylation | EYKRSKRSESREYVR HHHHHCCHHHCCCCC | 43.59 | 25561503 | |
| 422 | Phosphorylation | KRSKRSESREYVR-- HHHCCHHHCCCCC-- | 31.49 | 29654922 | |
| 425 | Phosphorylation | KRSESREYVR----- CCHHHCCCCC----- | 10.62 | 25561503 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RU17_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RU17_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RU17_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SRC33_ARATH | SR33 | physical | 10593939 | |
| SR45_ARATH | SR45 | physical | 10593939 | |
| RSZ21_ARATH | RSZP21 | physical | 9761791 | |
| RSZ22_ARATH | SRZ-22 | physical | 9761791 | |
| U2A2A_ARATH | ATU2AF65A | physical | 21798944 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-255 AND SER-282, ANDMASS SPECTROMETRY. | |
