UniProt ID | SRC33_ARATH | |
---|---|---|
UniProt AC | Q9SEU4 | |
Protein Name | Serine/arginine-rich SC35-like splicing factor SCL33 | |
Gene Name | SCL33 | |
Organism | Arabidopsis thaliana (Mouse-ear cress). | |
Sequence Length | 287 | |
Subcellular Localization | Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Colocalizes with spliceosome components. Follows a dynamic subcellular location during the cell cycle. Distributed throughout the cell on entry into mitosis, as the nuclear envelope breaks down. In | |
Protein Description | Involved in intron recognition and spliceosome assembly. Binds to multiple 5'-GAAG-3' repeats found in its third intron, suggesting autoregulation of alternative splicing. [PubMed: 22913769 May be necessary for accurate splicing of the 3' region of introns.] | |
Protein Sequence | MRGRSYTPSPPRGYGRRGRSPSPRGRYGGRSRDLPTSLLVRNLRHDCRQEDLRKSFEQFGPVKDIYLPRDYYTGDPRGFGFVQFMDPADAADAKHHMDGYLLLGRELTVVFAEENRKKPTEMRARERGGGRFRDRRRTPPRYYSRSRSPPPRRGRSRSRSGDYYSPPPRRHHPRSISPREERYDGRRSYSRSPASDGSRGRSLTPVRGKSRSLSPSPRRSISRSPRRSRSPSPKRNRSVSPRRSISRSPRRSRSPRRSRRSYTPEPARSRSQSPHGGQYDEDRSPSQ | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
5 | Phosphorylation | ---MRGRSYTPSPPR ---CCCCCCCCCCCC | 23776212 | ||
6 | Phosphorylation | --MRGRSYTPSPPRG --CCCCCCCCCCCCC | 23776212 | ||
7 | Phosphorylation | -MRGRSYTPSPPRGY -CCCCCCCCCCCCCC | 23776212 | ||
9 | Phosphorylation | RGRSYTPSPPRGYGR CCCCCCCCCCCCCCC | 23776212 | ||
14 | Phosphorylation | TPSPPRGYGRRGRSP CCCCCCCCCCCCCCC | 23776212 | ||
20 | Phosphorylation | GYGRRGRSPSPRGRY CCCCCCCCCCCCCCC | 23776212 | ||
22 | Phosphorylation | GRRGRSPSPRGRYGG CCCCCCCCCCCCCCC | 23776212 | ||
31 | Phosphorylation | RGRYGGRSRDLPTSL CCCCCCCCCCCCHHH | 25561503 | ||
144 | Phosphorylation | RTPPRYYSRSRSPPP CCCCCCCCCCCCCCC | 29654922 | ||
146 | Phosphorylation | PPRYYSRSRSPPPRR CCCCCCCCCCCCCCC | 29654922 | ||
148 | Phosphorylation | RYYSRSRSPPPRRGR CCCCCCCCCCCCCCC | 29654922 | ||
156 | Phosphorylation | PPPRRGRSRSRSGDY CCCCCCCCCCCCCCC | 25561503 | ||
158 | Phosphorylation | PRRGRSRSRSGDYYS CCCCCCCCCCCCCCC | 23111157 | ||
160 | Phosphorylation | RGRSRSRSGDYYSPP CCCCCCCCCCCCCCC | 30291188 | ||
163 | Phosphorylation | SRSRSGDYYSPPPRR CCCCCCCCCCCCCCC | 23111157 | ||
164 | Phosphorylation | RSRSGDYYSPPPRRH CCCCCCCCCCCCCCC | 23111157 | ||
165 | Phosphorylation | SRSGDYYSPPPRRHH CCCCCCCCCCCCCCC | 30291188 | ||
175 | Phosphorylation | PRRHHPRSISPREER CCCCCCCCCCCCHHH | 28011693 | ||
177 | Phosphorylation | RHHPRSISPREERYD CCCCCCCCCCHHHCC | 28011693 | ||
188 | Phosphorylation | ERYDGRRSYSRSPAS HHCCCCCCCCCCCCC | - | ||
190 | Phosphorylation | YDGRRSYSRSPASDG CCCCCCCCCCCCCCC | - | ||
202 | Phosphorylation | SDGSRGRSLTPVRGK CCCCCCCCCCCCCCC | 19376835 | ||
204 | Phosphorylation | GSRGRSLTPVRGKSR CCCCCCCCCCCCCCC | 19376835 | ||
238 | Phosphorylation | PSPKRNRSVSPRRSI CCCCCCCCCCCCHHC | - | ||
248 | Phosphorylation | PRRSISRSPRRSRSP CCHHCCCCCCCCCCC | - | ||
261 | Phosphorylation | SPRRSRRSYTPEPAR CCCCCCCCCCCCCCC | 29654922 | ||
262 | Phosphorylation | PRRSRRSYTPEPARS CCCCCCCCCCCCCCC | 19880383 | ||
263 | Phosphorylation | RRSRRSYTPEPARSR CCCCCCCCCCCCCCC | 19880383 | ||
269 | Phosphorylation | YTPEPARSRSQSPHG CCCCCCCCCCCCCCC | 29654922 | ||
271 | Phosphorylation | PEPARSRSQSPHGGQ CCCCCCCCCCCCCCC | - | ||
284 | Phosphorylation | GQYDEDRSPSQ---- CCCCCCCCCCC---- | - | ||
286 | Phosphorylation | YDEDRSPSQ------ CCCCCCCCC------ | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SRC33_ARATH !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SRC33_ARATH !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SRC33_ARATH !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
SRC28_ARATH | SCL28 | physical | 18674533 | |
SRC30_ARATH | SCL30 | physical | 18674533 | |
SL30A_ARATH | SCL30A | physical | 18674533 | |
SRC33_ARATH | SR33 | physical | 18674533 | |
RU17_ARATH | U1-70K | physical | 10593939 | |
SRC33_ARATH | SR33 | physical | 10593939 | |
SR45_ARATH | SR45 | physical | 10593939 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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