RSZ22_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RSZ22_ARATH
• UniProt AC: O81126
• Protein Name: Serine/arginine-rich splicing factor RSZ22
• Gene Name: RSZ22
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 200
• Subcellular Localization: Nucleus speckle . Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Shuttling between nucleolus, nucleoplasm and cytoplasm surrounding the nucleus. Nucleolus localization is dependent on phosphorylation state.
• Protein Description: Sequence-specific RNA-binding protein probably involved in pre-mRNA splicing. In vitro, can complement efficiently splicing-deficient mammalian SRSF7-depleted HeLa cell extract..
• Protein Sequence: MSRVYVGNLDPRVTERELEDEFRAFGVVRSVWVARRPPGYAFLDFEDPRDARDAIRALDGKNGWRVEQSHNRGERGGGGRGGDRGGGGGGRGGRGGSDLKCYECGETGHFARECRNRGGTGRRRSKSRSRTPPRYRRSPSYGRRSYSPRARSPPPPRRRSPSPPPARGRSYSRSPPPYRAREEVPYANGNGLKERRRSRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
138	Phosphorylation	TPPRYRRSPSYGRRS CCCCCCCCCCCCCCC		-
145	Phosphorylation	SPSYGRRSYSPRARS CCCCCCCCCCCCCCC		28011693
146	Phosphorylation	PSYGRRSYSPRARSP CCCCCCCCCCCCCCC		28011693
147	Phosphorylation	SYGRRSYSPRARSPP CCCCCCCCCCCCCCC		28011693
152	Phosphorylation	SYSPRARSPPPPRRR CCCCCCCCCCCCCCC		23776212
160	Phosphorylation	PPPPRRRSPSPPPAR CCCCCCCCCCCCCCC		23776212
162	Phosphorylation	PPRRRSPSPPPARGR CCCCCCCCCCCCCCC		23776212
170	Phosphorylation	PPPARGRSYSRSPPP CCCCCCCCCCCCCCC		19880383
171	Phosphorylation	PPARGRSYSRSPPPY CCCCCCCCCCCCCCC		23776212
172	Phosphorylation	PARGRSYSRSPPPYR CCCCCCCCCCCCCCC		19880383
174	Phosphorylation	RGRSYSRSPPPYRAR CCCCCCCCCCCCCCC		19880383
178	Phosphorylation	YSRSPPPYRAREEVP CCCCCCCCCCCCCCC		23776212
200	Phosphorylation	KERRRSRS------- HHHHHHCC-------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RSZ22_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RSZ22_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RSZ22_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RSZ22_ARATH	SRZ-22	physical	20237019
SRC30_ARATH	SCL30	physical	20237019
SL30A_ARATH	SCL30A	physical	20237019

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.