SC35_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SC35_ARATH
• UniProt AC: Q9FMG4
• Protein Name: Serine/arginine-rich splicing factor SC35
• Gene Name: SC35
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 303
• Subcellular Localization: Nucleus speckle .
• Protein Description: Probably involved in intron recognition and spliceosome assembly, but not involved in alternative splicing regulation of the SCL33 intron..
• Protein Sequence: MSHFGRSGPPDISDTYSLLVLNITFRTTADDLYPLFAKYGKVVDVFIPRDRRTGDSRGFAFVRYKYKDEAHKAVERLDGRVVDGREITVQFAKYGPNAEKISKGRVVEPPPKSRRSRSRSPRRSRSPRRSRSPPRRRSPRRSRSPRRRSRDDYREKDYRKRSRSRSYDRRERHEEKDRDHRRRTRSRSASPDEKRRVRGRYDNESRSHSRSLSASPARRSPRSSSPQKTSPAREVSPDKRSNERSPSPRRSLSPRSPALQKASPSKEMSPERRSNERSPSPGSPAPLRKVDAASRSQSPYAAE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MSHFGRSGPPDISD -CCCCCCCCCCCHHH		-
130	Phosphorylation	RSRSPRRSRSPPRRR CCCCCCCCCCCCCCC		23776212
132	Phosphorylation	RSPRRSRSPPRRRSP CCCCCCCCCCCCCCC		23776212
186	Phosphorylation	DHRRRTRSRSASPDE HHHHHHHHCCCCHHH		25561503
188	Phosphorylation	RRRTRSRSASPDEKR HHHHHHCCCCHHHHH		25561503
190	Phosphorylation	RTRSRSASPDEKRRV HHHHCCCCHHHHHCH		25561503
211	Phosphorylation	ESRSHSRSLSASPAR CCCCCCCCCCCCCCC		23776212
213	Phosphorylation	RSHSRSLSASPARRS CCCCCCCCCCCCCCC		23776212
215	Phosphorylation	HSRSLSASPARRSPR CCCCCCCCCCCCCCC		23776212
220	Phosphorylation	SASPARRSPRSSSPQ CCCCCCCCCCCCCCC		27288362
223	Phosphorylation	PARRSPRSSSPQKTS CCCCCCCCCCCCCCC		23776212
224	Phosphorylation	ARRSPRSSSPQKTSP CCCCCCCCCCCCCCC		23776212
225	Phosphorylation	RRSPRSSSPQKTSPA CCCCCCCCCCCCCCC		23776212
229	Phosphorylation	RSSSPQKTSPAREVS CCCCCCCCCCCCCCC		23776212
230	Phosphorylation	SSSPQKTSPAREVSP CCCCCCCCCCCCCCC		23776212
236	Phosphorylation	TSPAREVSPDKRSNE CCCCCCCCCCCCCCC		25561503
241	Phosphorylation	EVSPDKRSNERSPSP CCCCCCCCCCCCCCC		25561503
245	Phosphorylation	DKRSNERSPSPRRSL CCCCCCCCCCCCCCC		25561503
247	Phosphorylation	RSNERSPSPRRSLSP CCCCCCCCCCCCCCC		25561503
251	Phosphorylation	RSPSPRRSLSPRSPA CCCCCCCCCCCCCHH		23776212
253	Phosphorylation	PSPRRSLSPRSPALQ CCCCCCCCCCCHHHH		23776212
256	Phosphorylation	RRSLSPRSPALQKAS CCCCCCCCHHHHHCC		23776212
263	Phosphorylation	SPALQKASPSKEMSP CHHHHHCCCCCCCCH		23776212
265	Phosphorylation	ALQKASPSKEMSPER HHHHCCCCCCCCHHH		23776212
269	Phosphorylation	ASPSKEMSPERRSNE CCCCCCCCHHHHCCC		23776212
274	Phosphorylation	EMSPERRSNERSPSP CCCHHHHCCCCCCCC		19880383
278	Phosphorylation	ERRSNERSPSPGSPA HHHCCCCCCCCCCCC		23111157
280	Phosphorylation	RSNERSPSPGSPAPL HCCCCCCCCCCCCCH		23111157
283	Phosphorylation	ERSPSPGSPAPLRKV CCCCCCCCCCCHHHC		23111157
294	Phosphorylation	LRKVDAASRSQSPYA HHHCCHHHHCCCCCC		23776212
296	Phosphorylation	KVDAASRSQSPYAAE HCCHHHHCCCCCCCC		23776212
298	Phosphorylation	DAASRSQSPYAAE-- CHHHHCCCCCCCC--		23776212
300	Phosphorylation	ASRSQSPYAAE---- HHHCCCCCCCC----		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SC35_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SC35_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SC35_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRC30_ARATH	SCL30	physical	18674533
SL30A_ARATH	SCL30A	physical	18674533
SRC33_ARATH	SR33	physical	18674533
SC35_ARATH	SC35	physical	18674533

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.