| UniProt ID | CIPK9_ARATH | |
|---|---|---|
| UniProt AC | Q9MAM1 | |
| Protein Name | CBL-interacting serine/threonine-protein kinase 9 | |
| Gene Name | CIPK9 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 447 | |
| Subcellular Localization | Cytoplasm . Nucleus . Targeted to the tonoplast when interacting with CBL2 or CBL3. | |
| Protein Description | CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Involved in K(+) homeostasis under low-K(+) stress.. | |
| Protein Sequence | MSGSRRKATPASRTRVGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCPPWFSQGAKRVIKRILEPNPITRISIAELLEDEWFKKGYKPPSFDQDDEDITIDDVDAAFSNSKECLVTEKKEKPVSMNAFELISSSSEFSLENLFEKQAQLVKKETRFTSQRSASEIMSKMEETAKPLGFNVRKDNYKIKMKGDKSGRKGQLSVATEVFEVAPSLHVVELRKTGGDTLEFHKFYKNFSSGLKDVVWNTDAAAEEQKQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 88 | Phosphorylation | EIIEVMASKTKIYIV HHHHHHHCCCEEEEE | 23.82 | 19880383 | |
| 164 | Phosphorylation | KVSDFGLSAFSRQVR EECHHCHHHHCHHHH | 27.87 | - | |
| 178 | Phosphorylation | REDGLLHTACGTPNY HHCCCEECCCCCCCC | 24.50 | 30291188 | |
| 182 | Phosphorylation | LLHTACGTPNYVAPE CEECCCCCCCCCCHH | 14.30 | 23776212 | |
| 353 | Phosphorylation | TRFTSQRSASEIMSK HHHCCHHCHHHHHHH | 28.63 | 25561503 | |
| 355 | Phosphorylation | FTSQRSASEIMSKME HCCHHCHHHHHHHHH | 28.97 | 25561503 | |
| 417 | Phosphorylation | LRKTGGDTLEFHKFY EEECCCCCEEEHHHH | 31.31 | 25561503 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CIPK9_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CIPK9_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CIPK9_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| IAA11_ARATH | IAA11 | physical | 21798944 | |
| CNBL9_ARATH | CBL9 | physical | 21798944 | |
| UPP_ARATH | UPP | physical | 21798944 | |
| BRX_ARATH | BRX | physical | 21798944 | |
| KNAT1_ARATH | KNAT1 | physical | 21798944 | |
| CNBL1_ARATH | CBL1 | physical | 21798944 | |
| COG4_ARATH | AT4G01400 | physical | 21798944 | |
| PP298_ARATH | AT4G01400 | physical | 21798944 | |
| CNBL2_ARATH | CBL2 | physical | 21798944 | |
| CNBL1_ARATH | CBL1 | physical | 23109687 | |
| CNBL2_ARATH | CBL2 | physical | 23109687 | |
| CNBL3_ARATH | CBL3 | physical | 23109687 | |
| CNBL5_ARATH | CBL5 | physical | 23109687 | |
| CNBL6_ARATH | CBL6 | physical | 23109687 | |
| CNBL7_ARATH | CBL7 | physical | 23109687 | |
| CNBL8_ARATH | CBL8 | physical | 23109687 | |
| CNBL9_ARATH | CBL9 | physical | 23109687 | |
| CNBL7_ORYSJ | Os02g0291000 | physical | 24970010 | |
| CNBL4_ORYSJ | Os05g0534400 | physical | 24970010 | |
| CNBL5_ORYSJ | Os01g0598200 | physical | 24970010 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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