CNBL8_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CNBL8_ARATH
• UniProt AC: Q9FUQ7
• Protein Name: Calcineurin B-like protein 8
• Gene Name: CBL8
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 214
• Subcellular Localization: Cytoplasm . Nucleus . Cell membrane .
• Protein Description: Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner..
• Protein Sequence: MLAFVKCFSLKRAKHPRGYEDPHVLASETPFTVNEIEALHDLFKKLSTSIINDGLIHKEEFLLALFRNGSMQNLFADRVFYMFDRKRNGVIEFGEFVRSLSIFHPYTPEHEKSAFMFKLFDLHGTGFIEPHELKKMVGALLGETDLELSEESIEAIVEQTMLEVDTNKDGKIDEEEWKELVAKNPSILKNMTLPYLKEVTLAFPSFVLDSEVED

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
205	Phosphorylation	EVTLAFPSFVLDSEV HHEEECCHHHCCCCC	22.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CNBL8_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CNBL8_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CNBL8_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CIPKE_ARATH	SR1	physical	19832944
CIPKO_ARATH	SOS2	physical	22253446

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.