| UniProt ID | CIPKE_ARATH | |
|---|---|---|
| UniProt AC | Q9LZW4 | |
| Protein Name | CBL-interacting serine/threonine-protein kinase 14 | |
| Gene Name | CIPK14 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 442 | |
| Subcellular Localization | Cytoplasm . Nucleus . Targeted to the tonoplast when interacting with CBL2 or CBL3 and to the cell membrane when interacting with CBL8. | |
| Protein Description | CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).. | |
| Protein Sequence | MVDSDPVEFPPENRRGQLFGKYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRLRHPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSRRYFQQLISAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDLRRLLTRLLDTNPQTRITIEEIIHDPWFKQGYDDRMSKFHLEDSDMKLPADETDSEMGARRMNAFDIISGSPGFNLSGLFGDARKYDRVERFVSAWTAERVVERLEEIVSAENLTVAKKETWGMKIEGQKGNFAMVVEINQLTDELVMIEVRKRQRAAASGRDLWTDTLRPFFVELVHESDQTDPEPTQVHTTS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 47 | Phosphorylation | RSTATGQSVAIKVVS CCCCCCCEEEEEEEE | 18.17 | 19880383 | |
| 166 | Phosphorylation | KISDFGLSALTDQIR CHHHHCHHHHHCCCC | 22.93 | - | |
| 180 | Phosphorylation | RPDGLLHTLCGTPAY CCCCHHHHHCCCCCC | 24.58 | - | |
| 358 | Phosphorylation | ERLEEIVSAENLTVA HHHHHHHCHHCCEEE | 35.21 | 28295753 | |
| 363 | Phosphorylation | IVSAENLTVAKKETW HHCHHCCEEEEECCC | 29.96 | 28295753 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CIPKE_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CIPKE_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CIPKE_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CNBL2_ARATH | CBL2 | physical | 21685179 | |
| Y5738_ARATH | AT5G67385 | physical | 24528504 | |
| UBQ3_ARATH | UBQ3 | physical | 24528504 | |
| VAC14_ARATH | AT2G01690 | physical | 24528504 | |
| CIPKE_ARATH | SR1 | physical | 24823379 | |
| RVE2_ARATH | RVE2 | physical | 24823379 | |
| CNBL2_ARATH | CBL2 | physical | 25058458 | |
| CNBL3_ARATH | CBL3 | physical | 25058458 | |
| CNBL9_ARATH | CBL9 | physical | 25058458 | |
| CNBL2_ARATH | CBL2 | physical | 24521877 | |
| CNBL3_ARATH | CBL3 | physical | 24521877 | |
| CNBL7_ORYSJ | Os02g0291000 | physical | 24970010 | |
| CNBL4_ORYSJ | Os05g0534400 | physical | 24970010 | |
| CNBL5_ORYSJ | Os01g0598200 | physical | 24970010 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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