dbPTM

VAC14_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VAC14_ARATH
UniProt AC	Q9ZU97
Protein Name	Protein VAC14 homolog
Gene Name	VAC14
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	743
Subcellular Localization	Cytoplasm. Vacuole membrane Peripheral membrane protein.
Protein Description	The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Regulates the synthesis of PtdIns(3,5)P2 by positive activation of FAB1 and by controlling SAC/FIG4 localization (By similarity)..
Protein Sequence	MSDALSAIPAAVHRNLSDKLYEKRKNAALELENIVKNLTSSGDHDKISKVIEMLIKEFAKSPQANHRKGGLIGLAAVTVGLSTEAAQYLEQIVPPVINSFSDQDSRVRYYACEALYNIAKVVRGDFIIFFNKIFDALCKLSADSDANVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLKERMNVLNPYVRQFLVGWITVLDSVPDIDMLGFLPDFLDGLFNMLSDSSHEIRQQADSALSEFLQEIKNSPSVDYGRMAEILVQRAASPDEFTRLTAITWINEFVKLGGDQLVRYYADILGAILPCISDKEEKIRVVARETNEELRSIHVEPSDGFDVGAILSVARRQLSSEFEATRIEALNWISTLLNKHRTEVLCFLNDIFDTLLKALSDSSDDVVLLVLEVHAGVAKDPQHFRQLIVFLVHNFRADNSLLERRGALIVRRMCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILLTSPELSKLRELLKGSLVNREGKELFVALYTSWCHSPMAIISLCLLAQAYQHASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLLPQQSAAFKILRTRLKTVPTYSFSTGNQIGRATSGVPFSQYKHQNEDGDLEDDNINSSHQGINFAVRLQQFENVQNLHRGQARTRVNYSYHSSSSSTSKEVRRSEEQQQQQQQQQQQQQQQQRPPPSSTSSSVADNNRPPSRTSRKGPGQLQL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
623	Phosphorylation	GNQIGRATSGVPFSQ CCCCCCCCCCCCHHH	23776212
624	Phosphorylation	NQIGRATSGVPFSQY CCCCCCCCCCCHHHC	23776212
629	Phosphorylation	ATSGVPFSQYKHQNE CCCCCCHHHCCCCCC	23776212
631	Phosphorylation	SGVPFSQYKHQNEDG CCCCHHHCCCCCCCC	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VAC14_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VAC14_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VAC14_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of VAC14_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VAC14_ARATH

Related Literatures of Post-Translational Modification