RVE2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RVE2_ARATH
• UniProt AC: F4K5X6
• Protein Name: Protein REVEILLE 2
• Gene Name: RVE2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 287
• Subcellular Localization: Nucleus .
• Protein Description: Positive regulator for cold-responsive gene expression and cold tolerance. Part of a regulatory feedback loop that controls a subset of the circadian outputs and modulates the central oscillator. Negatively self-regulates its own expression..
• Protein Sequence: MAMQERCESLCSDELISSSDAFYLKTRKPYTITKQREKWTEAEHEKFVEALKLYGRAWRRIEEHVGTKTAVQIRSHAQKFFTKVARDFGVSSESIEIPPPRPKRKPMHPYPRKLVIPDAKEMVYAELTGSKLIQDEDNRSPTSVLSAHGSDGLGSIGSNSPNSSSAELSSHTEESLSLEAETKQSLKLFGKTFVVGDYNSSMSCDDSEDGKKKLYSETQSLQCSSSTSENAETEVVVSEFKRSERSAFSQLKSSVTEMNNMRGFMPYKKRVKVEENIDNVKLSYPLW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
216	Phosphorylation	DGKKKLYSETQSLQC CCCHHHHHHHHHEEC		24894044
218	Phosphorylation	KKKLYSETQSLQCSS CHHHHHHHHHEECCC		24894044
220	Phosphorylation	KLYSETQSLQCSSST HHHHHHHHEECCCCC		24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RVE2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RVE2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RVE2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NADB_ARATH	AO	physical	24823379
RVE2_ARATH	RVE2	physical	24823379

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.