CCA23_ARATH - dbPTM
CCA23_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CCA23_ARATH
UniProt AC Q38819
Protein Name Cyclin-A2-3
Gene Name CYCA2-3
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 450
Subcellular Localization Nucleus .
Protein Description Negatively regulates endocycles and acts as a regulator of ploidy levels in endoreduplication. [PubMed: 16415207 Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division]
Protein Sequence MGKENAVSRPFTRSLASALRASEVTSTTQNQQRVNTKRPALEDTRATGPNKRKKRAVLGEITNVNSNTAILEAKNSKQIKKGRGHGLASTSQLATSVTSEVTDLQSRTDAKVEVASNTAGNLSVSKGTDNTADNCIEIWNSRLPPRPLGRSASTAEKSAVIGSSTVPDIPKFVDIDSDDKDPLLCCLYAPEIHYNLRVSELKRRPLPDFMERIQKDVTQSMRGILVDWLVEVSEEYTLASDTLYLTVYLIDWFLHGNYVQRQQLQLLGITCMLIASKYEEISAPRIEEFCFITDNTYTRDQVLEMENQVLKHFSFQIYTPTPKTFLRRFLRAAQASRLSPSLEVEFLASYLTELTLIDYHFLKFLPSVVAASAVFLAKWTMDQSNHPWNPTLEHYTTYKASDLKASVHALQDLQLNTKGCPLSAIRMKYRQEKYKSVAVLTSPKLLDTLF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
47PhosphorylationALEDTRATGPNKRKK
CHHCHHCCCCCHHHH
50.2919880383
62PhosphorylationRAVLGEITNVNSNTA
HHHEEEEECCCCCCC
28.8928295753
66PhosphorylationGEITNVNSNTAILEA
EEEECCCCCCCEEEE
31.1328295753
68PhosphorylationITNVNSNTAILEAKN
EECCCCCCCEEEECC
18.2028295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CCA23_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CCA23_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CCA23_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDKA1_ARATHCDC2physical
20407024
CKB11_ARATHCDKB1;1physical
20407024
CDKD2_ARATHCAK4physical
20407024
CKS1_ARATHCKS1physical
20706207
CKB11_ARATHCDKB1;1physical
20706207
GENL1_ARATHAT1G01880physical
20706207
DPOD1_ARATHEMB2780physical
20706207
EF1G2_ARATHAT1G57720physical
20706207
EIF3I_ARATHTRIP-1physical
20706207
APX1_ARATHAPX1physical
20706207
AER_ARATHAERphysical
20706207
PPR87_ARATHPPR336physical
20706207
CDC23_ARATHAPC8physical
21798944
FRL3_ARATHAT5G48385physical
21798944
FAMA_ARATHFMAphysical
21798944
MED11_ARATHAT3G01435physical
21798944
2AB2C_ARATHAT5G28900physical
21798944
HS23M_ARATHHSP23.6-MITOphysical
21798944
CKS1_ARATHCKS1physical
19458112
GENL1_ARATHAT1G01880physical
19458112
DPOD1_ARATHEMB2780physical
19458112
EIF3I_ARATHTRIP-1physical
19458112
APX1_ARATHAPX1physical
19458112
EF1G2_ARATHAT1G57720physical
19458112
PPR87_ARATHPPR336physical
19458112
CKB11_ARATHCDKB1;1physical
19458112
AER_ARATHAERphysical
19458112

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CCA23_ARATH

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Related Literatures of Post-Translational Modification

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