EIF3I_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EIF3I_ARATH
• UniProt AC: Q38884
• Protein Name: Eukaryotic translation initiation factor 3 subunit I {ECO:0000255|HAMAP-Rule:MF_03008}
• Gene Name: TIF3I1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 328
• Subcellular Localization: Cytoplasm .
• Protein Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation..
• Protein Sequence: MRPILMKGHERPLTFLRYNREGDLLFSCAKDHTPTLWFADNGERLGTYRGHNGAVWCCDVSRDSSRLITGSADQTAKLWDVKSGKELFTFKFNAPTRSVDFAVGDRLAVITTDHFVDRTAAIHVKRIAEDPEEQDAESVLVLHCPDGKKRINRAVWGPLNQTIVSGGEDKVIRIWDAETGKLLKQSDEEVGHKKDITSLCKAADDSHFLTGSLDKTAKLWDMRTLTLLKTYTTVVPVNAVSLSPLLNHVVLGGGQDASAVTTTDHRAGKFEAKFYDKILQEEIGGVKGHFGPINALAFNPDGKSFSSGGEDGYVRLHHFDSDYFNIKI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
230	Phosphorylation	RTLTLLKTYTTVVPV HHHEEEEEECEEEEC	26.52	25368622
231	Phosphorylation	TLTLLKTYTTVVPVN HHEEEEEECEEEECC	9.99	25368622
232	Phosphorylation	LTLLKTYTTVVPVNA HEEEEEECEEEECCC	20.53	25368622
233	Phosphorylation	TLLKTYTTVVPVNAV EEEEEECEEEECCCC	14.75	25368622
258	Phosphorylation	LGGGQDASAVTTTDH ECCCCCCCCEECCCC	31.40	25368622
261	Phosphorylation	GQDASAVTTTDHRAG CCCCCCEECCCCCCC	24.56	25368622
262	Phosphorylation	QDASAVTTTDHRAGK CCCCCEECCCCCCCC	24.51	25368622
263	Phosphorylation	DASAVTTTDHRAGKF CCCCEECCCCCCCCE	22.05	25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EIF3I_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EIF3I_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EIF3I_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BRI1_ARATH	BRI1	physical	15998311

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.