CC183_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC183_HUMAN
• UniProt AC: Q5T5S1
• Protein Name: Coiled-coil domain-containing protein 183
• Gene Name: CCDC183
• Organism: Homo sapiens (Human).
• Sequence Length: 534
• Protein Sequence: MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEEWRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGINLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGKLKAAKKKKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MRRHSETDVEEQ ---CCCCCCCCHHHH		30622161
7	Phosphorylation	-MRRHSETDVEEQTQ -CCCCCCCCHHHHHH		30622161
123	Phosphorylation	RRGQKLESMQLELDS HCCHHHHHCCHHHHH		24961811
130	Phosphorylation	SMQLELDSLRSQPDA HCCHHHHHHHCCCCC		29978859
133	Phosphorylation	LELDSLRSQPDASKE HHHHHHHCCCCCCHH		29978859
186	Phosphorylation	LKTVLAGYPIELDKL HHHHHCCCCCCHHHH		27642862
208	Acetylation	CSELSDMKIMSQDAM HHHHCCCCHHCCHHH		24885355
211	Phosphorylation	LSDMKIMSQDAMMIT HCCCCHHCCHHHHHC		28509920
218	Phosphorylation	SQDAMMITDEVKRNM CCHHHHHCHHHHHHH		28509920
273	Phosphorylation	QMDLDFPSNLMSTET CCCCCCCCCCCCHHH		25693802
277	Phosphorylation	DFPSNLMSTETLKLR CCCCCCCCHHHHHHH		25693802
278	Phosphorylation	FPSNLMSTETLKLRR CCCCCCCHHHHHHHC		25693802
280	Phosphorylation	SNLMSTETLKLRRKE CCCCCHHHHHHHCCC		25693802
367	Phosphorylation	LKFRQKPSSISFKSV HHHHCCCCCCCHHHH		26074081
368	Phosphorylation	KFRQKPSSISFKSVE HHHCCCCCCCHHHHH		26074081
370	Phosphorylation	RQKPSSISFKSVEKK HCCCCCCCHHHHHHH		24719451
459	Phosphorylation	ADRVQMVSRTEEGDT HHHHEEEECCCCCCH		-
481	Phosphorylation	SSTLMEKYNTRISFE HHHHHHHHCCCCCCC		30266825
483	Phosphorylation	TLMEKYNTRISFENR HHHHHHCCCCCCCCC		30266825
486	Phosphorylation	EKYNTRISFENREED HHHCCCCCCCCCCCC		30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC183_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC183_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC183_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BCR_HUMAN	BCR	physical	26186194
NRBF2_HUMAN	NRBF2	physical	26186194
FOXP1_HUMAN	FOXP1	physical	26186194
RABE1_HUMAN	RABEP1	physical	26186194
CP131_HUMAN	CEP131	physical	26186194
NDEL1_HUMAN	NDEL1	physical	26186194
NDE1_HUMAN	NDE1	physical	26186194
RABX5_HUMAN	RABGEF1	physical	26186194
DIAP3_HUMAN	DIAPH3	physical	26186194
CCD14_HUMAN	CCDC14	physical	26186194
GRAP1_HUMAN	GRIPAP1	physical	26186194
ANFY1_HUMAN	ANKFY1	physical	26186194
PCM1_HUMAN	PCM1	physical	26186194
ARHGC_HUMAN	ARHGEF12	physical	26186194
PCNT_HUMAN	PCNT	physical	26186194
NUP85_HUMAN	NUP85	physical	26186194
E2F4_HUMAN	E2F4	physical	26186194
AP1B1_HUMAN	AP1B1	physical	26186194
TMF1_HUMAN	TMF1	physical	26186194
RUND1_HUMAN	RUNDC1	physical	26186194
AINX_HUMAN	INA	physical	26186194
RUFY1_HUMAN	RUFY1	physical	26186194
CCHCR_HUMAN	CCHCR1	physical	26186194
CEP55_HUMAN	CEP55	physical	26186194
TLE4_HUMAN	TLE4	physical	26186194
NUP37_HUMAN	NUP37	physical	26186194
CN080_HUMAN	C14orf80	physical	26186194
CCD14_HUMAN	CCDC14	physical	28514442
ARHGC_HUMAN	ARHGEF12	physical	28514442
TMF1_HUMAN	TMF1	physical	28514442
FOXP1_HUMAN	FOXP1	physical	28514442
GRAP1_HUMAN	GRIPAP1	physical	28514442
NRBF2_HUMAN	NRBF2	physical	28514442
RUND1_HUMAN	RUNDC1	physical	28514442
E2F4_HUMAN	E2F4	physical	28514442
CP131_HUMAN	CEP131	physical	28514442
PCM1_HUMAN	PCM1	physical	28514442
RABX5_HUMAN	RABGEF1	physical	28514442
CN080_HUMAN	C14orf80	physical	28514442
RABE1_HUMAN	RABEP1	physical	28514442
CCHCR_HUMAN	CCHCR1	physical	28514442
NDEL1_HUMAN	NDEL1	physical	28514442
DIAP3_HUMAN	DIAPH3	physical	28514442
NDE1_HUMAN	NDE1	physical	28514442
AINX_HUMAN	INA	physical	28514442
CEBPA_HUMAN	CEBPA	physical	28514442
BCR_HUMAN	BCR	physical	28514442
PCNT_HUMAN	PCNT	physical	28514442
RUFY1_HUMAN	RUFY1	physical	28514442
NUP85_HUMAN	NUP85	physical	28514442
AP1B1_HUMAN	AP1B1	physical	28514442
CEP55_HUMAN	CEP55	physical	28514442
TLE4_HUMAN	TLE4	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.