ZSC31_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSC31_HUMAN
• UniProt AC: Q96LW9
• Protein Name: Zinc finger and SCAN domain-containing protein 31
• Gene Name: ZSCAN31
• Organism: Homo sapiens (Human).
• Sequence Length: 406
• Subcellular Localization: Nucleus .
• Protein Description: May function as a transcription factor. May be involved in the development of multiple embryonic organs..
• Protein Sequence: MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFCYQETPGPREALSRLRELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPESGEEAVAVVEDLEQELSEPGNQAPDHEHGHSEVLLEDVEHLKVKQEPTDIQLQPMVTQLRYESFCLHQFQEQDGESIPENQELASKQEILKEMEHLGDSKLQRDVSLDSKYRETCKRDSKAEKQQAHSTGERRHRCNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSSLNEHRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLSSCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLKKHQKIHTGERP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASTEEQYDL -----CCCCHHCEEE		25002506
4	Phosphorylation	----MASTEEQYDLK ----CCCCHHCEEEE		25002506
14	Sumoylation	QYDLKIVKVEEDPIW CEEEEEEEEECCCCC		28112733
14	Sumoylation	QYDLKIVKVEEDPIW CEEEEEEEEECCCCC		-
58	Phosphorylation	PGPREALSRLRELCH CCHHHHHHHHHHHHH		-
149	Sumoylation	DVEHLKVKQEPTDIQ HHHHHCCCCCCCCCC		-
149	Sumoylation	DVEHLKVKQEPTDIQ HHHHHCCCCCCCCCC		28112733
153	Phosphorylation	LKVKQEPTDIQLQPM HCCCCCCCCCCCCCC		-
162	Phosphorylation	IQLQPMVTQLRYESF CCCCCCCCHHHHHHH		-
181	Phosphorylation	FQEQDGESIPENQEL HHHCCCCCCCCHHHH		28348404
191	Sumoylation	ENQELASKQEILKEM CHHHHHHHHHHHHHH		28112733
205	Sumoylation	MEHLGDSKLQRDVSL HHHHCCHHHHHHCCC		28112733
211	Phosphorylation	SKLQRDVSLDSKYRE HHHHHHCCCCHHHHH		25159151
215	Sumoylation	RDVSLDSKYRETCKR HHCCCCHHHHHHHHC		28112733
234	Phosphorylation	EKQQAHSTGERRHRC HHHHHHHHHHHHHHC		24719451
247	Phosphorylation	RCNECGKSFTKSSVL HCCCCCCCCCCCCEE		24719451
250	Sumoylation	ECGKSFTKSSVLIEH CCCCCCCCCCEEEEE		28112733
262	Phosphorylation	IEHQRIHTGEKPYEC EEEEEECCCCCCCCH		25159151
295	Phosphorylation	SHTGEKPYQCKECGK HCCCCCCEECCCCCC		-
318	Phosphorylation	TRHRRIHTGEKPYEC CCCCCCCCCCCCEEC		29496963
358	Sumoylation	YQCRECGKAFIQNAG EEHHHHHHHHHHHCC		28112733
374	Phosphorylation	FQHLRVHTGEKPYQC CCCCEECCCCCCCCC		-
389	Phosphorylation	SQCSKLFSKRTLLKK HHHHHHHCHHHHHHH		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSC31_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSC31_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSC31_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MTMR4_HUMAN	MTMR4	physical	28514442
PI51A_HUMAN	PIP5K1A	physical	28514442
CARF_HUMAN	CDKN2AIP	physical	28514442
DHX57_HUMAN	DHX57	physical	28514442
THA11_HUMAN	THAP11	physical	28514442
LENG8_HUMAN	LENG8	physical	28514442
RL26L_HUMAN	RPL26L1	physical	28514442
TRM1L_HUMAN	TRMT1L	physical	28514442
YTDC2_HUMAN	YTHDC2	physical	28514442
RRP5_HUMAN	PDCD11	physical	28514442
BBX_HUMAN	BBX	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.