ZN704_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN704_HUMAN
• UniProt AC: Q6ZNC4
• Protein Name: Zinc finger protein 704
• Gene Name: ZNF704
• Organism: Homo sapiens (Human).
• Sequence Length: 412
• Protein Sequence: MTFTFQSEDLKRDCGKKMSHQHVFSLAMEEDVKTADTKKASRILDHEKENTRSICLLEQKRKVVSSNIDVPPARKSSEELDMDKVTAAMVLTSLSTSPLVRSPPVRPNESLSGSWKEGGCVPSSTSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSPAQPDDGIDEAEASNLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGDSDYSDGEEDFYYTEIKLNTDSVADGLSSLAPVSPSQSLASPPTFPIPDSSRTETPCAKTETKLMTPLSRSAPTTLYLVHTDHAYQATPPVTIPGSAKFTPNGSSFSISWQSPPVTFTGIPVSPTHHPVGTGEQRQHAHTVLSSPPRGTVSLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	O-linked_Glycosylation	AMEEDVKTADTKKAS HHHCCCCCCCCHHHH	29.61	30379171
53	O-linked_Glycosylation	HEKENTRSICLLEQK HCHHCCCEEEEHHHH	18.67	30379171
76	Phosphorylation	DVPPARKSSEELDMD CCCCCCCCCCCCCHH	37.11	29255136
77	Phosphorylation	VPPARKSSEELDMDK CCCCCCCCCCCCHHH	37.82	29255136
86	Phosphorylation	ELDMDKVTAAMVLTS CCCHHHHHHHHHHHH	17.91	27251275
92	Phosphorylation	VTAAMVLTSLSTSPL HHHHHHHHHHCCCCC	19.06	27251275
93	Phosphorylation	TAAMVLTSLSTSPLV HHHHHHHHHCCCCCC	19.03	28102081
95	Phosphorylation	AMVLTSLSTSPLVRS HHHHHHHCCCCCCCC	26.97	25850435
96	Phosphorylation	MVLTSLSTSPLVRSP HHHHHHCCCCCCCCC	39.39	25850435
97	Phosphorylation	VLTSLSTSPLVRSPP HHHHHCCCCCCCCCC	16.92	29507054
102	Phosphorylation	STSPLVRSPPVRPNE CCCCCCCCCCCCCCC	26.52	23663014
110	Phosphorylation	PPVRPNESLSGSWKE CCCCCCCCCCCCCCC	34.18	27794612
112	Phosphorylation	VRPNESLSGSWKEGG CCCCCCCCCCCCCCC	39.81	27794612
114	Phosphorylation	PNESLSGSWKEGGCV CCCCCCCCCCCCCCC	31.44	25849741
146	Phosphorylation	QSNPSTPSPPLSADS CCCCCCCCCCCCCCC	38.96	28348404
159	Phosphorylation	DSFKPFRSPAQPDDG CCCCCCCCCCCCCCC	25.60	27732954
173	Phosphorylation	GIDEAEASNLLFDEP CCCHHHHHHCCCCCC	21.37	27732954
188	Phosphorylation	IPRKRKNSMKVMFKC CCCCCCCHHHHHHHH	24.02	30576142
206	Phosphorylation	NCGKVLSTAAGIQKH HHHHHHHHHHHHHHH	19.16	23403867
212	Ubiquitination	STAAGIQKHIRTIHL HHHHHHHHHHEEEEC	38.79	-
225	Phosphorylation	HLGRVGDSDYSDGEE ECCCCCCCCCCCCCC	32.30	22617229
227	Phosphorylation	GRVGDSDYSDGEEDF CCCCCCCCCCCCCCE	16.77	29802988
228	Phosphorylation	RVGDSDYSDGEEDFY CCCCCCCCCCCCCEE	44.10	22617229
235	Phosphorylation	SDGEEDFYYTEIKLN CCCCCCEEEEEEEEC	23.07	28102081
243	Phosphorylation	YTEIKLNTDSVADGL EEEEEECCCCCCCCH	39.84	29978859
245	Phosphorylation	EIKLNTDSVADGLSS EEEECCCCCCCCHHH	19.71	29978859
251	Phosphorylation	DSVADGLSSLAPVSP CCCCCCHHHCCCCCC	28.92	29978859
252	Phosphorylation	SVADGLSSLAPVSPS CCCCCHHHCCCCCCC	33.33	29802988
257	Phosphorylation	LSSLAPVSPSQSLAS HHHCCCCCCCCCCCC	20.13	26657352
259	Phosphorylation	SLAPVSPSQSLASPP HCCCCCCCCCCCCCC	25.54	29978859
261	Phosphorylation	APVSPSQSLASPPTF CCCCCCCCCCCCCCC	30.18	29978859
264	Phosphorylation	SPSQSLASPPTFPIP CCCCCCCCCCCCCCC	36.38	25921289
278	Phosphorylation	PDSSRTETPCAKTET CCCCCCCCCCCCCCC	24.05	-
285	Phosphorylation	TPCAKTETKLMTPLS CCCCCCCCCCCCCCC	34.41	-
294	Phosphorylation	LMTPLSRSAPTTLYL CCCCCCCCCCCEEEE	34.91	30266825
297	Phosphorylation	PLSRSAPTTLYLVHT CCCCCCCCEEEEEEC	29.20	30266825
298	Phosphorylation	LSRSAPTTLYLVHTD CCCCCCCEEEEEECC	16.61	30266825
300	Phosphorylation	RSAPTTLYLVHTDHA CCCCCEEEEEECCCC	12.46	30576142
304	Phosphorylation	TTLYLVHTDHAYQAT CEEEEEECCCCEECC	23.23	27732954
308	Phosphorylation	LVHTDHAYQATPPVT EEECCCCEECCCCEE	8.68	27732954
311	Phosphorylation	TDHAYQATPPVTIPG CCCCEECCCCEECCC	16.76	27732954
315	Phosphorylation	YQATPPVTIPGSAKF EECCCCEECCCCEEE	27.51	28102081
335	Phosphorylation	SFSISWQSPPVTFTG CEEEEEECCCEEEEC	25.55	28348404
346	Phosphorylation	TFTGIPVSPTHHPVG EEECCCCCCCCCCCC	20.80	28348404
363	Phosphorylation	EQRQHAHTVLSSPPR CCCCCEEEECCCCCC	24.75	28152594
366	Phosphorylation	QHAHTVLSSPPRGTV CCEEEECCCCCCCCE	36.14	30266825
367	Phosphorylation	HAHTVLSSPPRGTVS CEEEECCCCCCCCEE	34.46	30266825
372	Phosphorylation	LSSPPRGTVSLRKPR CCCCCCCCEECCCCC	14.27	28152594
374	Phosphorylation	SPPRGTVSLRKPRGE CCCCCCEECCCCCCC	23.46	28152594

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN704_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN704_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN704_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FBW1A_HUMAN	BTRC	physical	28514442
FBW1B_HUMAN	FBXW11	physical	28514442
SP30L_HUMAN	SAP30L	physical	28514442
SIN3A_HUMAN	SIN3A	physical	28514442
SDS3_HUMAN	SUDS3	physical	28514442
ING2_HUMAN	ING2	physical	28514442
ARI4A_HUMAN	ARID4A	physical	28514442
SAP30_HUMAN	SAP30	physical	28514442
SP130_HUMAN	SAP130	physical	28514442
ARI4B_HUMAN	ARID4B	physical	28514442
BRM1L_HUMAN	BRMS1L	physical	28514442
FBXW5_HUMAN	FBXW5	physical	28514442
BRMS1_HUMAN	BRMS1	physical	28514442
TPM2_HUMAN	TPM2	physical	28514442
CUL1_HUMAN	CUL1	physical	28514442
DCP1B_HUMAN	DCP1B	physical	28514442
IMDH1_HUMAN	IMPDH1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.