YKY4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YKY4_SCHPO
• UniProt AC: Q9P7G0
• Protein Name: Uncharacterized NOC2 family protein C1142.04
• Gene Name: SPAC1142.04
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 707
• Subcellular Localization: Nucleus, nucleolus .
• Protein Sequence: MVKLSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVLTSDTIQQWQKLLETNHSLTTLQKVVQAFKAAAFLNEEEAEDLKYTISDSKVFNDLLLLAIQYVPKVLNYHVPIQEDAKGKKFINTDSKVLPKLRPVLKSYGFSILRLLEGMTDAKNISLLLREAQNVLPYMITYRKFLKQFTQATVEVWSSTRDDSVRFSAVVLLRTLCLTADITLLEFVLKEVYLGMARQSAYTTVHTLDKINFLKNSAVNLFLLDAESCYLIGFRYIRQLAITLRNTIHQPSKDSRKPVQSWSYVHSLDFWARLLSQAAWLSREKGVASELQSLVYPLVQIALGVIMSSPSSQLFPMRFHIIRSLIYLSRHTGVFIPLAPSLFEVLDSSYVSRKAKASTLKPLDFDVELRASSSYLRTKVYQDGLIDQLLELLSEYYVLYATDISFPELVIPAIVRSKRFAKRSKNAKLNRGLLTLVNRLEQQSKFMTEKRNQQKFAPIDSDSVEQFAQTIDWQQTPLGIYVVTQRQTREEQRKLIRESVQQDQEHKEQMRQKKKQALKSDDIELDDLSEEEAEDIDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
112	Phosphorylation	QDSTSESSEEEEDGL CCCCCCCCHHHHHHH	45.00	28889911
276	Phosphorylation	KLRPVLKSYGFSILR HHHHHHHHCCHHHHH	26.74	25720772
277	Phosphorylation	LRPVLKSYGFSILRL HHHHHHHCCHHHHHH	22.17	25720772
698	Phosphorylation	DIELDDLSEEEAEDI CCCHHHCCHHHHHHC	50.37	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YKY4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YKY4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YKY4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YKY4_SCHPO	SPAC1142.04	physical	26771498
E2AK1_SCHPO	hri1	physical	26771498
BECN1_SCHPO	atg6	physical	26771498
YD4B_SCHPO	SPAC22H10.11c	physical	26771498
YEJJ_SCHPO	abo1	physical	26771498
YEK9_SCHPO	SPAC4F10.09c	physical	26771498
TEA3_SCHPO	tea3	physical	26771498
YH04_SCHPO	SPBC1685.04	physical	26771498
YH7H_SCHPO	SPBC16G5.17	physical	26771498
MCP5_SCHPO	mcp5	physical	26771498
YGNB_SCHPO	nap2	physical	26771498
SGM1_SCHPO	SPBC365.07c	physical	26771498
CLR3_SCHPO	clr3	physical	26771498
TAS3_SCHPO	tas3	physical	26771498
YHI5_SCHPO	abo2	physical	26771498
YOFG_SCHPO	SPBP4H10.16c	physical	26771498
YCO6_SCHPO	nap1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-112, AND MASSSPECTROMETRY.
PubMed: 18257517