dbPTM

YEK9_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YEK9_SCHPO
UniProt AC	O36021
Protein Name	Uncharacterized protein C4F10.09c
Gene Name	SPAC4F10.09c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	860
Subcellular Localization
Protein Description
Protein Sequence	MATLYPKPKRGQKIIFNEEGEGTIDTKPQGVMFDPGVPWYNIPLPELHEDKKFVNVDHVSELETRGLLLLKEDSERFSETLGHGTADKRMLQTLISSGTTSDRISALTLLVQESPIHAVKALETLLSICSKKSRNEATQAITTLKDLFIGGLLPDRKLKYMKQQSCLGSKNVTDKHLMVWAFESFLKSFYFKYIQIIEALSFDALLFVKSQMVSTIYDLLKAKPEQEQNLLKLLINKLGDKENKIASKASYSILQLEASHPAMKLVITKEIERFIFAPSTSRTSCYYTLITLNQTVLTHKQVDVANLLIEIYFVFFTKLLFALEKEEVADAPTLEKKSLQSDSKNKKSQKRKKDEDLRKEAEENVNSRVISAVLTGVNRAYPFAEVNSEKFDKHMNTLFAITHTASFNTSVQVLMLIFQASASRDFISDRYYKSLYESLLDPRLTTSSKQSLYLNLLYKSLIIDNNIPRVRAFIKRMVQVSAWQQPPLVTGLFHVMHQLVIATTALRSMFTNAEIHDFDGDEEEVFKDVEEDDVSEDQKVDSDKDGKLSDKQSHSAYVVGNVSVSTKKEHLSYDGRKRDPQYSNADGSCLWEIHPFLNHFHPTVSLLAKSLVYGEKILGKPNLSLHTLNHFLDKFAYRNPKKSAAARGHSIMQPLAGGLSKGYVPGSTYSGVPMNSEQFTSKKQEEIPVDELFFYRFFNDKYIKGKQARKTKVDRDEEGEIDEDEVWKALVDSKPQLEMDEEESDFDSEEMDKAMTDMGSDSEQSADENDNESMASEEKPMFSDEENLSEIAHSEDEFDDTVDFFEDENDLLPFNETDDEEEIQTVDHSETHSHKKKKRKAIKDLPVFADAESYAHLLEN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
535	Phosphorylation	DVEEDDVSEDQKVDS CCCCCCCCCCCCCCC	42.31	25720772
733	Phosphorylation	VWKALVDSKPQLEMD HHHHHHCCCCCCCCC	38.46	21712547
744	Phosphorylation	LEMDEEESDFDSEEM CCCCCCCCCCCHHHH	47.02	28889911
748	Phosphorylation	EEESDFDSEEMDKAM CCCCCCCHHHHHHHH	35.14	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YEK9_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YEK9_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YEK9_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TEA3_SCHPO	tea3	physical	26771498
CBH1_SCHPO	cbh1	physical	26771498
YGNB_SCHPO	nap2	physical	26771498
TAS3_SCHPO	tas3	physical	26771498
YHI5_SCHPO	abo2	physical	26771498
KCY_SCHPO	SPCC1795.05c	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YEK9_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-744 AND SER-748, ANDMASS SPECTROMETRY.	18257517 [Abstract]