dbPTM

YD4B_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YD4B_SCHPO
UniProt AC	Q10304
Protein Name	Uncharacterized protein C22H10.11c
Gene Name	SPAC22H10.11c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	629
Subcellular Localization
Protein Description
Protein Sequence	MALTNGRIEEYDIQNGYQNTEEIKKLPAELNFPVDFDKMPTFIFQEERQKLDLPLSDSEENQFHDFSDSKLSLGFEIGRSKEKFVDEKPFYSNKEPLKINSWKKSSSHPKSKEVSNGLLKVSTPPTEFVKRENAGIRRRSSNQGSFALEAPKILKRDAMFKESWKNKCFISPQKDNQGFSKSKHLSTYEGETENGFSTSTEEEEEEEEDIVSASWVDNLDMDMASFNSHRERFLTEHVNMDERSDDDFLLGLISSDSSVDDHDNEQDDVDLIGWECFFDDSSDELNTLSHQADDEGDTTDEETPELQNNKLLNLSTPKKSFGQTPRIKTELSESPNSQRTLLSAVPTPLELSAELAYKEDLTSLASRANISDNSTGLTPTLAKATLAQPVSTVVSVASFELDPRLNITQPKPPVMGTWAKEPNHLIGIIDGKHSHSLHHDKFDACTKGENTANNGYGPQTLNETSEEPSLDDILDTSLLQPSTQTDLQEENSVSFAQEDNSLSRWEKIPIGTFRKNQYIKSMARRDELIRDEWFTLAIKTREKRRHKINATGMTTTNSVPLRPKSRKARRALKKKARKMTFRQMHSDFQSALEDEHNDGSYLDNDYETVGLGLGPELSPLFEILESSGY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Phosphorylation	QKLDLPLSDSEENQF HHCCCCCCCCCCCCC	36.83	24763107
58	Phosphorylation	LDLPLSDSEENQFHD CCCCCCCCCCCCCCC	43.35	21712547
67	Phosphorylation	ENQFHDFSDSKLSLG CCCCCCCCCCCEECC	47.21	21712547
69	Phosphorylation	QFHDFSDSKLSLGFE CCCCCCCCCEECCEE	34.01	21712547
122	Phosphorylation	SNGLLKVSTPPTEFV HCCCEEECCCCHHHH	33.34	29996109
123	Phosphorylation	NGLLKVSTPPTEFVK CCCEEECCCCHHHHC	35.95	28889911
140	Phosphorylation	NAGIRRRSSNQGSFA CCCCCCCCCCCCCEE	31.65	29996109
141	Phosphorylation	AGIRRRSSNQGSFAL CCCCCCCCCCCCEEE	31.21	25720772
145	Phosphorylation	RRSSNQGSFALEAPK CCCCCCCCEEECHHH	9.51	29996109
171	Phosphorylation	WKNKCFISPQKDNQG HCCCCEECCCCCCCC	10.88	24763107
315	Phosphorylation	NNKLLNLSTPKKSFG HCCEECCCCCCCCCC	41.40	24763107
316	Phosphorylation	NKLLNLSTPKKSFGQ CCEECCCCCCCCCCC	42.15	21712547
329	Phosphorylation	GQTPRIKTELSESPN CCCCCCCCCCCCCCC	39.52	29996109
332	Phosphorylation	PRIKTELSESPNSQR CCCCCCCCCCCCCCH	29.78	29996109
334	Phosphorylation	IKTELSESPNSQRTL CCCCCCCCCCCCHHH	26.46	28889911
337	Phosphorylation	ELSESPNSQRTLLSA CCCCCCCCCHHHHHC	25.15	29996109
343	Phosphorylation	NSQRTLLSAVPTPLE CCCHHHHHCCCCCHH	30.27	21712547
378	Phosphorylation	SDNSTGLTPTLAKAT CCCCCCCCHHHHHHH	18.64	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YD4B_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YD4B_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YD4B_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
YGV4_SCHPO	SPBC354.04	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YD4B_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-334, AND MASSSPECTROMETRY.	18257517 [Abstract]