WFDC2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WFDC2_HUMAN
• UniProt AC: Q14508
• Protein Name: WAP four-disulfide core domain protein 2
• Gene Name: WFDC2
• Organism: Homo sapiens (Human).
• Sequence Length: 124
• Subcellular Localization: Secreted .
• Protein Description: Broad range protease inhibitor..
• Protein Sequence: MPACRLGPLAAALLLSLLLFGFTLVSGTGAEKTGVCPELQADQNCTQECVSDSECADNLKCCSAGCATFCSLPNDKEGSCPQVNINFPQLGLCRDQCQVDSQCPGQMKCCRNGCGKVSCVTPNF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
44	N-linked_Glycosylation	PELQADQNCTQECVS CHHCCCCCCCHHCCC	31.20	16740002

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WFDC2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WFDC2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WFDC2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PTN_HUMAN	PTN	physical	16169070
WDR81_HUMAN	WDR81	physical	28514442
PDIA5_HUMAN	PDIA5	physical	28514442
WDR91_HUMAN	WDR91	physical	28514442
CRAC1_HUMAN	CRTAC1	physical	28514442
PTPRF_HUMAN	PTPRF	physical	28514442
EMC4_HUMAN	EMC4	physical	28514442
IF1AX_HUMAN	EIF1AX	physical	28514442
GRN_HUMAN	GRN	physical	28514442
FKBP7_HUMAN	FKBP7	physical	28514442
BTBD1_HUMAN	BTBD1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

N-linked Glycosylation

"Identification of N-linked glycoproteins in human saliva byglycoprotein capture and mass spectrometry.";
Ramachandran P., Boontheung P., Xie Y., Sondej M., Wong D.T.,Loo J.A.;
J. Proteome Res. 5:1493-1503(2006).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-44, AND MASS SPECTROMETRY.
PubMed: 16740002