TSSK6_HUMAN - dbPTM
TSSK6_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TSSK6_HUMAN
UniProt AC Q9BXA6
Protein Name Testis-specific serine/threonine-protein kinase 6
Gene Name TSSK6 {ECO:0000312|EMBL:AAH14611.1}
Organism Homo sapiens (Human).
Sequence Length 273
Subcellular Localization
Protein Description Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity)..
Protein Sequence MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMSGDKLLSELGYKLG
CCHHHHHHHHHHHHC		41.0130622161
22PhosphorylationGRTIGEGSYSKVKVA
CCCCCCCCCCEEEEE		23.1830622161
23PhosphorylationRTIGEGSYSKVKVAT
CCCCCCCCCEEEEEE		24.3030622161
24PhosphorylationTIGEGSYSKVKVATS
CCCCCCCCEEEEEEC		32.4430622161
251PhosphorylationIAELLQFSPSARPSA
HHHHHHCCCCCCCCH		12.6530622161
253PhosphorylationELLQFSPSARPSAGQ
HHHHCCCCCCCCHHH		35.3930622161
257PhosphorylationFSPSARPSAGQVARN
CCCCCCCCHHHHHHH		39.2130622161
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TSSK6_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TSSK6_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TSSK6_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MBP_HUMANMBPphysical
15870294
HS90A_HUMANHSP90AA1physical
15870294
HSP7C_HUMANHSPA8physical
15870294
HSP74_HUMANHSPA4physical
15870294
H2A2C_HUMANHIST2H2ACphysical
15870294
H31_HUMANHIST1H3Aphysical
15870294
H2AX_HUMANH2AFXphysical
15870294
H12_BOVINHIST1H1Cphysical
15870294
A4_HUMANAPPphysical
21832049
TCPB_HUMANCCT2physical
25852190
TCPG_HUMANCCT3physical
25852190
TCPD_HUMANCCT4physical
25852190
TCPE_HUMANCCT5physical
25852190
TCPZ_HUMANCCT6Aphysical
25852190
TCPH_HUMANCCT7physical
25852190
TCPQ_HUMANCCT8physical
25852190
FKBP5_HUMANFKBP5physical
25852190
TCPA_HUMANTCP1physical
25852190
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TSSK6_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory