THI2_YEAST - dbPTM
THI2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID THI2_YEAST
UniProt AC P38141
Protein Name Thiamine biosynthesis regulatory protein
Gene Name THI2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 450
Subcellular Localization Nucleus .
Protein Description Positive regulator of thiamine biosynthesis..
Protein Sequence MVNSKRQQRSKKVASSSKVPPTKGRTFTGCWACRFKKRRCDENRPICSLCAKHGDNCSYDIRLMWLEENIYKVRKHSLISSLQARKSKSKPLCQKISKSRFKQMTHFRQLSPPTSDCEDSVHEASKETTLPNDNTFTISVRRLKIYNNAVASVFGSMTNRDYTQKRIDKKLDELLNMVENDISVVNLNCSKHGPYSVFRANPAAVTSALTDQLPSPGHSMSSAEETTTAALSSPPEDSTSLIDIIQGKIFGILWFNCYGNMILNRQEYTTWFINKMRNSLTTEFIRFLGKIIDDPDINMASCLFKECIARWSCVDWQSIAITMLVIIHGYTCPNLTKLLRVWFLQQKLLRFSMYPLVNFIINNTQDLDVLYHCNGLLGNADLFEDPYQDELTSELHVLVTERLVNSWKDTILQQLCSCQDTTLSCSQLRYWQLQLKCNQQFYKDVYAMQD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
16PhosphorylationRSKKVASSSKVPPTK
HCHHHHHCCCCCCCC		25.1727214570
77PhosphorylationIYKVRKHSLISSLQA
HHHHHHHHHHHHHHH		30.3628889911
152PhosphorylationIYNNAVASVFGSMTN
EECCHHHHHHHHCCC		16.0427017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of THI2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of THI2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of THI2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RNQ1_YEASTRNQ1genetic
22529103
THI3_YEASTTHI3genetic
27015653
MAK16_YEASTMAK16genetic
27708008
PDC2_YEASTPDC2genetic
27708008
MPPA_YEASTMAS2genetic
27708008
ORC6_YEASTORC6genetic
27708008
KTHY_YEASTCDC8genetic
27708008
ERO1_YEASTERO1genetic
27708008
NSL1_YEASTNSL1genetic
27708008
VPS41_YEASTVPS41genetic
27708008
ENO1_YEASTENO1genetic
27708008
ELM1_YEASTELM1genetic
27708008
PFD6_YEASTYKE2genetic
27708008
THI7_YEASTTHI7genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of THI2_YEAST

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Related Literatures of Post-Translational Modification

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