T184A_HUMAN - dbPTM
T184A_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID T184A_HUMAN
UniProt AC Q6ZMB5
Protein Name Transmembrane protein 184A
Gene Name TMEM184A
Organism Homo sapiens (Human).
Sequence Length 413
Subcellular Localization Cell membrane
Multi-pass membrane protein . Cytoplasm, perinuclear region . Cytoplasmic vesicle membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Endosome . Cytoplasmic vesicle, secretory vesicle membrane .
Protein Description Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity)..
Protein Sequence MSNVSGILETAGVPLVSANWPQPSPPPAVPAGPQMDHMGNSSQGAPWLFLTSALARGVSGIFVWTALVLTCHQIYLHLRSYTVPQEQRYIIRLLLIVPIYAFDSWLSLLLLGDHQYYVYFDSVRDCYEAFVIYSFLSLCFQYLGGEGAIMAEIRGKPIKSSCLYGTCCLRGMTYSIGFLRFCKQATLQFCLVKPVMAVTTIILQAFGKYHDGDFNVRSGYLYVTLIYNASVSLALYALFLFYFTTRELLRPFQPVLKFLTIKAVIFLSFWQGLLLAILERCGVIPEVETSGGNKLGAGTLAAGYQNFIICVEMLFASVALRYAFPCQVYAEKKENSPAPPAPMQSISSGIRETVSPQDIVQDAIHNFSPAYQHYTQQATHEAPRPGTHPSGGSGGSRKSRSLEKRMLIPSEDL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
336PhosphorylationYAEKKENSPAPPAPM
EEECCCCCCCCCCCC		24.4321815630
345PhosphorylationAPPAPMQSISSGIRE
CCCCCCCHHHHCCCC		20.4128857561
347PhosphorylationPAPMQSISSGIRETV
CCCCCHHHHCCCCCC		27.9728857561
348PhosphorylationAPMQSISSGIRETVS
CCCCHHHHCCCCCCC		36.2528857561
355PhosphorylationSGIRETVSPQDIVQD
HCCCCCCCHHHHHHH		25.0225159151
368PhosphorylationQDAIHNFSPAYQHYT
HHHHHHCCHHHHHHH		17.5925159151
371PhosphorylationIHNFSPAYQHYTQQA
HHHCCHHHHHHHHHC		10.1327642862
374PhosphorylationFSPAYQHYTQQATHE
CCHHHHHHHHHCCCC		7.2427642862
399PhosphorylationGSGGSRKSRSLEKRM
CCCCCCCCCCCCCCC		26.4527067055
401PhosphorylationGGSRKSRSLEKRMLI
CCCCCCCCCCCCCCC		48.2327067055
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of T184A_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of T184A_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of T184A_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AL4A1_HUMANALDH4A1physical
28514442
PDP2_HUMANPDP2physical
28514442
HIBCH_HUMANHIBCHphysical
28514442
T2FB_HUMANGTF2F2physical
28514442
MAOM_HUMANME2physical
28514442
SYYM_HUMANYARS2physical
28514442
CAF17_HUMANIBA57physical
28514442
KCD15_HUMANKCTD15physical
28514442
RBM38_HUMANRBM38physical
28514442
ASSY_HUMANASS1physical
28514442
RIR1_HUMANRRM1physical
28514442
ISCU_HUMANISCUphysical
28514442
BI2L1_HUMANBAIAP2L1physical
28514442
NRDC_HUMANNRD1physical
28514442
LYRM7_HUMANLYRM7physical
28514442
DGUOK_HUMANDGUOKphysical
28514442
CAV1_HUMANCAV1physical
28514442
MUTA_HUMANMUTphysical
28514442
GLYM_HUMANSHMT2physical
28514442
RTF2_HUMANRTFDC1physical
28514442
ACSF3_HUMANACSF3physical
28514442
AFAD_HUMANMLLT4physical
28514442
MCMBP_HUMANMCMBPphysical
28514442
MBOA7_HUMANMBOAT7physical
28514442
PDXD1_HUMANPDXDC1physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of T184A_HUMAN

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Related Literatures of Post-Translational Modification

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