| UniProt ID | RTF2_HUMAN | |
|---|---|---|
| UniProt AC | Q9BY42 | |
| Protein Name | Protein RTF2 homolog | |
| Gene Name | RTFDC1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 306 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MGCDGGTIPKRHELVKGPKKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKAASHIKSIKNVTELKLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLRCCGCVFSERALKEIKAEVCHTCGAAFQEDDVIMLNGTKEDVDVLKTRMEERRLRAKLEKKTKKPKAAESVSKPDVSEEAPGPSKVKTGKPEEASLDSREKKTNLAPKSTAMNESSSGKAGKPPCGATKRSIADSEESEAYKSLFTTHSSAKRSKEESAHWVTHTSYCF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Ubiquitination | CDGGTIPKRHELVKG CCCCCCCCHHHHHCC | - | ||
| 16 | Acetylation | PKRHELVKGPKKVEK CCHHHHHCCCCCCCC | 25953088 | ||
| 59 | Ubiquitination | ELGRLYNKDAVIEFL HHHHHCCHHHHHHHH | - | ||
| 70 | Phosphorylation | IEFLLDKSAEKALGK HHHHCCHHHHHHHHH | 21964256 | ||
| 77 | Sumoylation | SAEKALGKAASHIKS HHHHHHHHHHHHHHH | - | ||
| 83 | Sumoylation | GKAASHIKSIKNVTE HHHHHHHHHCCCCCE | - | ||
| 86 | Sumoylation | ASHIKSIKNVTELKL HHHHHHCCCCCEEEC | - | ||
| 86 | Ubiquitination | ASHIKSIKNVTELKL HHHHHHCCCCCEEEC | - | ||
| 89 | Ubiquitination | IKSIKNVTELKLSDN HHHCCCCCEEECCCC | - | ||
| 92 | Sumoylation | IKNVTELKLSDNPAW CCCCCEEECCCCCCC | - | ||
| 99 | Ubiquitination | KLSDNPAWEGDKGNT ECCCCCCCCCCCCCC | - | ||
| 100 | Phosphorylation | LSDNPAWEGDKGNTK CCCCCCCCCCCCCCC | - | ||
| 103 | Acetylation | NPAWEGDKGNTKGDK CCCCCCCCCCCCCCC | 23954790 | ||
| 107 | Sumoylation | EGDKGNTKGDKHDDL CCCCCCCCCCCHHHH | - | ||
| 107 | Ubiquitination | EGDKGNTKGDKHDDL CCCCCCCCCCCHHHH | - | ||
| 110 | Acetylation | KGNTKGDKHDDLQRA CCCCCCCCHHHHHHH | 25953088 | ||
| 113 | Sumoylation | TKGDKHDDLQRARFI CCCCCHHHHHHHHHH | - | ||
| 113 | Ubiquitination | TKGDKHDDLQRARFI CCCCCHHHHHHHHHH | - | ||
| 116 | Sumoylation | DKHDDLQRARFICPV CCHHHHHHHHHHHCE | - | ||
| 116 | Ubiquitination | DKHDDLQRARFICPV CCHHHHHHHHHHHCE | - | ||
| 122 | Sumoylation | QRARFICPVVGLEMN HHHHHHHCEECEEEC | - | ||
| 122 | Ubiquitination | QRARFICPVVGLEMN HHHHHHHCEECEEEC | - | ||
| 133 | Acetylation | LEMNGRHRFCFLRCC EEECCCEEEHHHHHC | - | ||
| 133 | Ubiquitination | LEMNGRHRFCFLRCC EEECCCEEEHHHHHC | - | ||
| 183 | Sumoylation | KEDVDVLKTRMEERR HHHHHHHHHHHHHHH | - | ||
| 207 | Phosphorylation | KKPKAAESVSKPDVS CCCCHHHHCCCCCCC | 25159151 | ||
| 209 | Phosphorylation | PKAAESVSKPDVSEE CCHHHHCCCCCCCCC | 28348404 | ||
| 210 | Sumoylation | KAAESVSKPDVSEEA CHHHHCCCCCCCCCC | - | ||
| 210 | Acetylation | KAAESVSKPDVSEEA CHHHHCCCCCCCCCC | 26051181 | ||
| 213 | Sumoylation | ESVSKPDVSEEAPGP HHCCCCCCCCCCCCC | - | ||
| 213 | Ubiquitination | ESVSKPDVSEEAPGP HHCCCCCCCCCCCCC | - | ||
| 214 | Phosphorylation | SVSKPDVSEEAPGPS HCCCCCCCCCCCCCC | 25627689 | ||
| 221 | Phosphorylation | SEEAPGPSKVKTGKP CCCCCCCCCCCCCCC | 29743597 | ||
| 222 | Acetylation | EEAPGPSKVKTGKPE CCCCCCCCCCCCCCC | 25953088 | ||
| 224 | Sumoylation | APGPSKVKTGKPEEA CCCCCCCCCCCCCCC | - | ||
| 225 | Phosphorylation | PGPSKVKTGKPEEAS CCCCCCCCCCCCCCC | 21406692 | ||
| 227 | Sumoylation | PSKVKTGKPEEASLD CCCCCCCCCCCCCCC | - | ||
| 232 | Phosphorylation | TGKPEEASLDSREKK CCCCCCCCCCCHHHH | 21406692 | ||
| 235 | Phosphorylation | PEEASLDSREKKTNL CCCCCCCCHHHHHCC | 25159151 | ||
| 237 | Phosphorylation | EASLDSREKKTNLAP CCCCCCHHHHHCCCC | - | ||
| 239 | Sumoylation | SLDSREKKTNLAPKS CCCCHHHHHCCCCCH | - | ||
| 240 | Acetylation | LDSREKKTNLAPKST CCCHHHHHCCCCCHH | - | ||
| 240 | Sumoylation | LDSREKKTNLAPKST CCCHHHHHCCCCCHH | - | ||
| 245 | Sumoylation | KKTNLAPKSTAMNES HHHCCCCCHHHCCCC | - | ||
| 246 | Phosphorylation | KTNLAPKSTAMNESS HHCCCCCHHHCCCCC | 24114839 | ||
| 252 | Phosphorylation | KSTAMNESSSGKAGK CHHHCCCCCCCCCCC | 24114839 | ||
| 253 | Phosphorylation | STAMNESSSGKAGKP HHHCCCCCCCCCCCC | 24114839 | ||
| 254 | Sumoylation | TAMNESSSGKAGKPP HHCCCCCCCCCCCCC | - | ||
| 254 | Phosphorylation | TAMNESSSGKAGKPP HHCCCCCCCCCCCCC | - | ||
| 255 | Phosphorylation | AMNESSSGKAGKPPC HCCCCCCCCCCCCCC | - | ||
| 256 | Acetylation | MNESSSGKAGKPPCG CCCCCCCCCCCCCCC | 26051181 | ||
| 257 | Sumoylation | NESSSGKAGKPPCGA CCCCCCCCCCCCCCC | - | ||
| 262 | Phosphorylation | GKAGKPPCGATKRSI CCCCCCCCCCCHHCC | - | ||
| 265 | Phosphorylation | GKPPCGATKRSIADS CCCCCCCCHHCCCCH | 24114839 | ||
| 266 | Acetylation | KPPCGATKRSIADSE CCCCCCCHHCCCCHH | 25953088 | ||
| 268 | O-linked_Glycosylation | PCGATKRSIADSEES CCCCCHHCCCCHHHH | 30379171 | ||
| 268 | Phosphorylation | PCGATKRSIADSEES CCCCCHHCCCCHHHH | 25159151 | ||
| 269 | Sumoylation | CGATKRSIADSEESE CCCCHHCCCCHHHHH | - | ||
| 272 | Phosphorylation | TKRSIADSEESEAYK CHHCCCCHHHHHHHH | 28985074 | ||
| 275 | Sumoylation | SIADSEESEAYKSLF CCCCHHHHHHHHHHH | - | ||
| 275 | Ubiquitination | SIADSEESEAYKSLF CCCCHHHHHHHHHHH | - | ||
| 275 | Phosphorylation | SIADSEESEAYKSLF CCCCHHHHHHHHHHH | - | ||
| 278 | Phosphorylation | DSEESEAYKSLFTTH CHHHHHHHHHHHHHC | - | ||
| 279 | Sumoylation | SEESEAYKSLFTTHS HHHHHHHHHHHHHCC | - | ||
| 280 | Phosphorylation | EESEAYKSLFTTHSS HHHHHHHHHHHHCCH | 28555341 | ||
| 280 | O-linked_Glycosylation | EESEAYKSLFTTHSS HHHHHHHHHHHHCCH | 30379171 | ||
| 283 | Phosphorylation | EAYKSLFTTHSSAKR HHHHHHHHHCCHHHC | 29396449 | ||
| 284 | Phosphorylation | AYKSLFTTHSSAKRS HHHHHHHHCCHHHCC | 29396449 | ||
| 286 | Ubiquitination | KSLFTTHSSAKRSKE HHHHHHCCHHHCCHH | - | ||
| 286 | Phosphorylation | KSLFTTHSSAKRSKE HHHHHHCCHHHCCHH | 25159151 | ||
| 287 | Phosphorylation | SLFTTHSSAKRSKEE HHHHHCCHHHCCHHH | 23401153 | ||
| 289 | Acetylation | FTTHSSAKRSKEESA HHHCCHHHCCHHHHC | 25953088 | ||
| 296 | Ubiquitination | KRSKEESAHWVTHTS HCCHHHHCCHHCCCC | - | ||
| 298 | Phosphorylation | SKEESAHWVTHTSYC CHHHHCCHHCCCCCC | 18212344 | ||
| 309 | Ubiquitination | TSYCF---------- CCCCC---------- | - | ||
| 309 | Sumoylation | TSYCF---------- CCCCC---------- | - | ||
| 314 | Phosphorylation | --------------- --------------- | - | ||
| 316 | Phosphorylation | ----------------- ----------------- | - | ||
| 317 | Phosphorylation | ------------------ ------------------ | 20068231 | ||
| 319 | Ubiquitination | -------------------- -------------------- | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RTF2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RTF2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RTF2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ABL1_HUMAN | ABL1 | physical | 26344197 | |
| CBS_HUMAN | CBS | physical | 26344197 | |
| PYRG1_HUMAN | CTPS1 | physical | 26344197 | |
| DDX17_HUMAN | DDX17 | physical | 26344197 | |
| SYLC_HUMAN | LARS | physical | 26344197 | |
| PIN4_HUMAN | PIN4 | physical | 26344197 | |
| TRM1_HUMAN | TRMT1 | physical | 26344197 | |
| OGT1_HUMAN | OGT | physical | 26496610 | |
| PAPD5_HUMAN | PAPD5 | physical | 26496610 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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