STXB6_HUMAN - dbPTM
STXB6_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID STXB6_HUMAN
UniProt AC Q8NFX7
Protein Name Syntaxin-binding protein 6
Gene Name STXBP6
Organism Homo sapiens (Human).
Sequence Length 210
Subcellular Localization Cytoplasm . Membrane
Peripheral membrane protein .
Protein Description Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis..
Protein Sequence MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSVTNKKPTQASITKVKQFEGSTSFVRRSQWMLEQLRQVNGIDPNGDSAEFDLLFENAFDQWVASTASEKCTFFQILHHTCQRYLTDRKPEFINCQSKIMGGNSILHSAADSVTSAVQKASQALNERGERLGRAEEKTEDLKNSAQQFAETAHKLAMKHKC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSAKSAISK
------CCHHHHHHH
44.3922814378
8PhosphorylationMSAKSAISKEIFAPL
CCHHHHHHHHHCCCC
24.7724076635
9UbiquitinationSAKSAISKEIFAPLD
CHHHHHHHHHCCCCC
49.0330230243
21UbiquitinationPLDERMLGAVQVKRR
CCCHHHCCCHHCCCC
17.8530230243
26UbiquitinationMLGAVQVKRRTKKKI
HCCCHHCCCCCCCCC
21.0430230243
38UbiquitinationKKIPFLATGGQGEYL
CCCCEEEECCCCCEE
43.9530230243
56UbiquitinationCLSVTNKKPTQASIT
EEEECCCCCCCCCEE
56.2030230243
63O-linked_GlycosylationKPTQASITKVKQFEG
CCCCCCEEEEEEECC
27.5630059200
64UbiquitinationPTQASITKVKQFEGS
CCCCCEEEEEEECCC
45.8530230243
66UbiquitinationQASITKVKQFEGSTS
CCCEEEEEEECCCCH
51.3130230243
68UbiquitinationSITKVKQFEGSTSFV
CEEEEEEECCCCHHH
10.7330230243
76UbiquitinationEGSTSFVRRSQWMLE
CCCCHHHHHHHHHHH
30.4430230243
78UbiquitinationSTSFVRRSQWMLEQL
CCHHHHHHHHHHHHH
20.0330230243
78PhosphorylationSTSFVRRSQWMLEQL
CCHHHHHHHHHHHHH
20.0324076635
146PhosphorylationPEFINCQSKIMGGNS
HHHHCCCCHHCCCCH
26.75-
147MalonylationEFINCQSKIMGGNSI
HHHCCCCHHCCCCHH
15.7226320211
153PhosphorylationSKIMGGNSILHSAAD
CHHCCCCHHHHHHHH
29.7827251275
157PhosphorylationGGNSILHSAADSVTS
CCCHHHHHHHHHHHH
23.00-
161PhosphorylationILHSAADSVTSAVQK
HHHHHHHHHHHHHHH
23.67-
191UbiquitinationEEKTEDLKNSAQQFA
HHHHHHHHHHHHHHH
62.2729967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of STXB6_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of STXB6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of STXB6_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ALS2_HUMANALS2physical
28514442
STX7_HUMANSTX7physical
28514442
STX1A_HUMANSTX1Aphysical
28514442
STX3_HUMANSTX3physical
28514442
STX4_HUMANSTX4physical
28514442
SNAG_HUMANNAPGphysical
28514442
STX8_HUMANSTX8physical
28514442
VTI1B_HUMANVTI1Bphysical
28514442
STX12_HUMANSTX12physical
28514442
ATG7_HUMANATG7physical
28514442
STX6_HUMANSTX6physical
28514442
SNAA_HUMANNAPAphysical
28514442
SNP23_HUMANSNAP23physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of STXB6_HUMAN

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Related Literatures of Post-Translational Modification

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