RDX_DROME - dbPTM
RDX_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RDX_DROME
UniProt AC Q9VFP2
Protein Name Protein roadkill
Gene Name rdx
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 829
Subcellular Localization Nucleus .
Protein Description Involved in segment polarity. In complex with gft/CUL3, promotes ubiquitination of ci and its subsequent degradation by the proteasome, which results in hh signaling attenuation. This regulation may be important during eye formation for proper packing of ommatidia into a hexagonal array..
Protein Sequence MFEPYVKIKKKRSVNEIYENENLEQQQHHLQQQQQQPATSDNCCCENGEPQNAPEVATATVAATSVAATSAAATVATGAAASSSSSGNCSRLQQLISTPPVLLRRSSLQQQQHQQQQHHPHTPAATATPPQQQQQQQAAPSVLQQHLGHLNYESGATAAAAATAAAAAATVATSRSGSATLAQHLATPSNILQAAFGSSNLQHILTRSAPSPSSSAISSNNCSSACAGNTHYNGGNSNSGSSSSNSNHHSNSIIASRLFGAASSSSSSSSSSASASSSSVAASSSSSSHHLHSHHSALTNSITNRINQSIRRHLNQQQHHHPLSASSSSASASPSASTSSSSSYQQSSVQQQHYNCAHPAQQQQHHHHHHSSSSSSSSSSSSSHHHHNSSSSSNSNNQQQPQQSPLCLVLLVKCPNSKEFCNAAANFCDKRLPVNECQASQTARVTSNLHASSSTMAVSRVPSPPLPEVNTPVAENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFDNEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYTGKAPNLEKMADDLLAAADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFINTHATDVMETSGWQNMITTHSHLIAEAFRALATQQIPPIGPPRKRVKMS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of RDX_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RDX_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RDX_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RDX_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EWG_DROMEewgphysical
14605208
RPC6_DROMECG5380physical
14605208
WDR26_DROMECG7611physical
14605208
TCTP_DROMETctpphysical
14605208
RS3_DROMERpS3physical
14605208
RL22_DROMERpL22physical
14605208
SOG_DROMEsogphysical
14605208
CI_DROMEciphysical
16740475
UBIQP_DROMEUbi-p63Ephysical
26263855
GPTC1_DROMECG8833physical
25242320
RDX_DROMErdxphysical
26263855
CI_DROMEciphysical
24603360
CI_DROMEciphysical
26120032
CI_DROMEciphysical
23747190

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RDX_DROME

loading...

Related Literatures of Post-Translational Modification

TOP