UniProt ID | RDX_DROME | |
---|---|---|
UniProt AC | Q9VFP2 | |
Protein Name | Protein roadkill | |
Gene Name | rdx | |
Organism | Drosophila melanogaster (Fruit fly). | |
Sequence Length | 829 | |
Subcellular Localization | Nucleus . | |
Protein Description | Involved in segment polarity. In complex with gft/CUL3, promotes ubiquitination of ci and its subsequent degradation by the proteasome, which results in hh signaling attenuation. This regulation may be important during eye formation for proper packing of ommatidia into a hexagonal array.. | |
Protein Sequence | MFEPYVKIKKKRSVNEIYENENLEQQQHHLQQQQQQPATSDNCCCENGEPQNAPEVATATVAATSVAATSAAATVATGAAASSSSSGNCSRLQQLISTPPVLLRRSSLQQQQHQQQQHHPHTPAATATPPQQQQQQQAAPSVLQQHLGHLNYESGATAAAAATAAAAAATVATSRSGSATLAQHLATPSNILQAAFGSSNLQHILTRSAPSPSSSAISSNNCSSACAGNTHYNGGNSNSGSSSSNSNHHSNSIIASRLFGAASSSSSSSSSSASASSSSVAASSSSSSHHLHSHHSALTNSITNRINQSIRRHLNQQQHHHPLSASSSSASASPSASTSSSSSYQQSSVQQQHYNCAHPAQQQQHHHHHHSSSSSSSSSSSSSHHHHNSSSSSNSNNQQQPQQSPLCLVLLVKCPNSKEFCNAAANFCDKRLPVNECQASQTARVTSNLHASSSTMAVSRVPSPPLPEVNTPVAENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFDNEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYTGKAPNLEKMADDLLAAADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFINTHATDVMETSGWQNMITTHSHLIAEAFRALATQQIPPIGPPRKRVKMS | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
---|---|---|---|---|---|---|
Oops, there are no PTM records of RDX_DROME !! |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RDX_DROME !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RDX_DROME !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RDX_DROME !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
EWG_DROME | ewg | physical | 14605208 | |
RPC6_DROME | CG5380 | physical | 14605208 | |
WDR26_DROME | CG7611 | physical | 14605208 | |
TCTP_DROME | Tctp | physical | 14605208 | |
RS3_DROME | RpS3 | physical | 14605208 | |
RL22_DROME | RpL22 | physical | 14605208 | |
SOG_DROME | sog | physical | 14605208 | |
CI_DROME | ci | physical | 16740475 | |
UBIQP_DROME | Ubi-p63E | physical | 26263855 | |
GPTC1_DROME | CG8833 | physical | 25242320 | |
RDX_DROME | rdx | physical | 26263855 | |
CI_DROME | ci | physical | 24603360 | |
CI_DROME | ci | physical | 26120032 | |
CI_DROME | ci | physical | 23747190 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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