WDR26_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WDR26_DROME
• UniProt AC: Q7K0L4
• Protein Name: WD repeat-containing protein 26 homolog
• Gene Name: CG7611
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 630
• Subcellular Localization: Cytoplasm . Mitochondrion .
• Protein Description: G-beta-like protein involved in cell signal transduction (By similarity)..
• Protein Sequence: MQSTSSTSSGSCSRPLEGSTLNSGGSAENVARDGGSGDDSVGIGDENPSGSSAATNGHDSKHNGFIVNNNGSSSRIVDGENNRENTSCSGVQLDKSNQEIIRLIGQYLHDVGLDKSVQTLMLESGCYLEHPSATKFREHVLMGDWSKADSDLKDLEPLIDNGKLATITEMKFILLEQKYLEHLDDGNPLDALHVLRSELTPLQHNITRVHQLSSYMMCSTNQDLYQRAKWEGKGILSRALVMERLQTFMPPSVMMSPRRLRTLLQQAVELQSQHCPCHDMAWETNLETVSLLTDHCCTTDGFPMQTIQILTDHCDEVWFCKFSPDGLKLATGSKDSTVIIWDVDPYKLTLKHRRVLDGQAQLSVSFVSWSPDSKLILVGGTEDSHELYIWNVDDGKLVVKFSQSLEDSLACGAFSRDGARFVCGGQKGQLYLCDLNGTIVDSWEGVRVNSIAFRADNKTILAADNHYRIRGYNFDSPRSDFDILREPHPIMTFSINSADRLALLNVSNQGLHLWDIEDKCLVRRFQGIRQSNFAIHSCFGGVNESFVASGSEDKVVYIWHIKREEPLAKLAGHTKTVNCVSWNPVYPSLLASASDDATVRIWGPKPNGSSATTESDDCSSSSSSSSWNMT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	STLNSGGSAENVARD CCCCCCCCHHHCCCC	35.62	19429919
36	Phosphorylation	NVARDGGSGDDSVGI HCCCCCCCCCCCCCC	44.57	19429919
40	Phosphorylation	DGGSGDDSVGIGDEN CCCCCCCCCCCCCCC	27.30	23607784
72	Phosphorylation	FIVNNNGSSSRIVDG EEECCCCCCCEEECC	27.54	19429919
73	Phosphorylation	IVNNNGSSSRIVDGE EECCCCCCCEEECCC	25.65	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WDR26_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WDR26_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WDR26_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36 AND SER-40, AND MASSSPECTROMETRY.
PubMed: 18327897