RL22_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL22_DROME
• UniProt AC: P50887
• Protein Name: 60S ribosomal protein L22
• Gene Name: RpL22
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 299
• Protein Sequence: MAPTAKTNKGDTKTAAAKPAEKKAAPAAAAAKGKVEKPKAEAAKPAAAAAKNVKKASEAAKDVKAAAAAAKPAAAKPAAAKPAAASKDAGKKAPAAAAPKKDAKAAAAPAPAKAAPAKKAASTPAAAPPAKKAAPAKAAAPAAAAPAPAAAAPAVAKPAPKPKAKAAPAPSKVVKKNVLRGKGQKKKKVSLRFTIDCTNIAEDSIMDVADFEKYIKARLKVNGKVNNLGNNVTFERSKLKLIVSSDVHFSKAYLKYLTKKYLKKNSLRDWIRVVANEKDSYELRYFRISSNDDEDDDAE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Phosphorylation	AKNVKKASEAAKDVK HHHHHHHHHHHHHHH	36.33	22817900
86	Phosphorylation	AAKPAAASKDAGKKA HCCCCHHCCHHCCCC	26.75	22817900
122	Phosphorylation	APAKKAASTPAAAPP CCCHHHCCCCCCCCC	39.52	22817900
123	Phosphorylation	PAKKAASTPAAAPPA CCHHHCCCCCCCCCH	16.54	21082442
172	Acetylation	KAAPAPSKVVKKNVL CCCCCCCHHHHHHHH	50.41	21791702
289	Phosphorylation	ELRYFRISSNDDEDD EEEEEEEECCCCCCC	20.87	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL22_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL22_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL22_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RL22_DROME	RpL22	physical	14605208
NOM1_DROME	CG9004	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.