LOK_DROME - dbPTM
LOK_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LOK_DROME
UniProt AC O61267
Protein Name Ovarian-specific serine/threonine-protein kinase Lok
Gene Name lok
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 476
Subcellular Localization Nucleus speckle . Speckled subnuclear compartment.
Protein Description May have a role in germline establishment..
Protein Sequence MARDTQGTQGTQSQASNIWTQVESQPMEKIVWGRLYGKNIKIKSLGTSSKYRIIYTHSSFSVDLNNDEFTAGRGEANDLILTLNDLPEKILTRISKVHFIIKRANCELTNPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPTYKAFVFKDLSPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEPPTKRSRR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of LOK_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LOK_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LOK_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LOK_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PP12_DROMEPp1-87Bphysical
15575970
DIMM_DROMEdimmphysical
15575970
DOA_DROMEDoaphysical
15575970
Y9776_DROMECG9776physical
15575970
ATR_DROMEmei-41genetic
18845846
CHK1_DROMEgrpgenetic
18845846
CALM_DROMECamgenetic
18612247
MELT_DROMEmeltgenetic
18612247
POLO_DROMEpologenetic
12804777
TRX_DROMEtrxgenetic
18612247
ESM7_DROMEE(spl)m7-HLHgenetic
18612247
NHK1_DROMEballgenetic
18612247
MPIP_DROMEstggenetic
12804777
MCM3_DROMEMcm3physical
22853956
MCM6_DROMEMcm6physical
22853956
PSF2_DROMEPsf2physical
22853956
LOK_DROMElokphysical
22853956
MCM4_DROMEdpaphysical
22853956

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LOK_DROME

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Related Literatures of Post-Translational Modification

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