HXC9_HUMAN - dbPTM
HXC9_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HXC9_HUMAN
UniProt AC P31274
Protein Name Homeobox protein Hox-C9
Gene Name HOXC9
Organism Homo sapiens (Human).
Sequence Length 260
Subcellular Localization Nucleus.
Protein Description Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis..
Protein Sequence MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
119AcetylationGGRHYALKPDAYPGR
CCCEEECCCCCCCCC		32.4523236377
137PhosphorylationCGPGEGRSYPDYMYG
CCCCCCCCCCCHHCC		52.4524719451
141PhosphorylationEGRSYPDYMYGSPGE
CCCCCCCHHCCCCCH		6.4224719451
143PhosphorylationRSYPDYMYGSPGELR
CCCCCHHCCCCCHHH		14.2827251275
145PhosphorylationYPDYMYGSPGELRDR
CCCHHCCCCCHHHCC		16.5521815630
156PhosphorylationLRDRAPQTLPSPEAD
HHCCCCCCCCCHHHH		39.3126657352
159PhosphorylationRAPQTLPSPEADALA
CCCCCCCCHHHHHHC		38.1930266825
168PhosphorylationEADALAGSKHKEEKA
HHHHHCCCCCHHHHC		26.4429978859
180PhosphorylationEKADLDPSNPVANWI
HHCCCCCCCHHHHHH		54.13-
199PhosphorylationTRKKRCPYTKYQTLE
CCCCCCCCCCCEEEH		21.3528634298
200PhosphorylationRKKRCPYTKYQTLEL
CCCCCCCCCCEEEHH		14.3928634298
202PhosphorylationKRCPYTKYQTLELEK
CCCCCCCCEEEHHHH		10.0328634298
204PhosphorylationCPYTKYQTLELEKEF
CCCCCCEEEHHHHHH		21.0728634298
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HXC9_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HXC9_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HXC9_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HXC13_HUMANHOXC13physical
20211142
HXD1_HUMANHOXD1physical
20211142
HXD9_HUMANHOXD9physical
20211142
RPB4_HUMANPOLR2Dphysical
20211142
PO2F1_HUMANPOU2F1physical
20211142
TTP_HUMANZFP36physical
20211142
PCGF2_HUMANPCGF2physical
20211142
NMI_HUMANNMIphysical
20211142
IRF9_HUMANIRF9physical
20211142
TF2AY_HUMANGTF2A1Lphysical
20211142
CBX6_HUMANCBX6physical
20211142
ZN384_HUMANZNF384physical
20211142
LPXN_HUMANLPXNphysical
25416956
IDE_HUMANIDEphysical
26186194
SAHH3_HUMANAHCYL2physical
26186194
SAHH2_HUMANAHCYL1physical
26186194
SAHH3_HUMANAHCYL2physical
28514442
IDE_HUMANIDEphysical
28514442
SAHH2_HUMANAHCYL1physical
28514442
NDUS1_HUMANNDUFS1physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HXC9_HUMAN

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Related Literatures of Post-Translational Modification

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