| UniProt ID | HST4_SCHPO | |
|---|---|---|
| UniProt AC | Q9UR39 | |
| Protein Name | NAD-dependent protein deacetylase hst4 | |
| Gene Name | hst4 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 415 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | NAD-dependent histone deacetylase, which contributes to both telomeric and centromeric silencing, proper cell cycle progression, DNA damage control, recombination, and genomic maintenance.. | |
| Protein Sequence | MKVEEHVPLIQESRKRKCQSSENASKRQQLLSKLPLRLHTGNENVDLSPLVSAIRKAKRIVVVTGAGISCDAGIPDFRSSEGLFSSLRAEYKLNCSGKELFDGSVYRDLKSVNIFHAMIRKLHMLSNNARPTDFHLFLSQLAQESKLLRLYTQNIDFLETRLEGLQTCIPLPQSAPWPTTIPLHGTLEVVSCTRCSFLKKFNPDIFDRNGVTVCPDCKTENEVRRIAGKRSVIEGCLRPRIVLYNEIHPDSESIGSVCSQDLKSRPDCLIVAGTSCKIPGVKRIIKEMSNCVHKQKGNVIWLNYDEPTKDFLNLCDLVVQGDLQIAIRRLKPLLDAPSWKLKSHSAKRTSKQKSSEQTKITSSTKITKAIGLNTKSNDSSKKDNTSFQLHQVLNSIEIPKVEIKQEVEYATPSPL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of HST4_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HST4_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HST4_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HST4_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RAD3_SCHPO | rad3 | genetic | 18344406 | |
| RHP9_SCHPO | crb2 | genetic | 18344406 | |
| MRC1_SCHPO | mrc1 | genetic | 18344406 | |
| CDS1_SCHPO | cds1 | genetic | 18344406 | |
| CHK1_SCHPO | chk1 | genetic | 18344406 | |
| MAG1_SCHPO | mag1 | genetic | 18344406 | |
| APN2_SCHPO | apn2 | genetic | 18344406 | |
| FEN1_SCHPO | rad2 | genetic | 18344406 | |
| RAD13_SCHPO | rad13 | genetic | 18344406 | |
| RAD50_SCHPO | rad50 | genetic | 18344406 | |
| YAS5_SCHPO | mms1 | genetic | 21183410 | |
| AMS2_SCHPO | ams2 | genetic | 23195958 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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