UniProt ID | HST4_SCHPO | |
---|---|---|
UniProt AC | Q9UR39 | |
Protein Name | NAD-dependent protein deacetylase hst4 | |
Gene Name | hst4 | |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
Sequence Length | 415 | |
Subcellular Localization | Nucleus, nucleolus . | |
Protein Description | NAD-dependent histone deacetylase, which contributes to both telomeric and centromeric silencing, proper cell cycle progression, DNA damage control, recombination, and genomic maintenance.. | |
Protein Sequence | MKVEEHVPLIQESRKRKCQSSENASKRQQLLSKLPLRLHTGNENVDLSPLVSAIRKAKRIVVVTGAGISCDAGIPDFRSSEGLFSSLRAEYKLNCSGKELFDGSVYRDLKSVNIFHAMIRKLHMLSNNARPTDFHLFLSQLAQESKLLRLYTQNIDFLETRLEGLQTCIPLPQSAPWPTTIPLHGTLEVVSCTRCSFLKKFNPDIFDRNGVTVCPDCKTENEVRRIAGKRSVIEGCLRPRIVLYNEIHPDSESIGSVCSQDLKSRPDCLIVAGTSCKIPGVKRIIKEMSNCVHKQKGNVIWLNYDEPTKDFLNLCDLVVQGDLQIAIRRLKPLLDAPSWKLKSHSAKRTSKQKSSEQTKITSSTKITKAIGLNTKSNDSSKKDNTSFQLHQVLNSIEIPKVEIKQEVEYATPSPL | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
---|---|---|---|---|---|---|
Oops, there are no PTM records of HST4_SCHPO !! |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HST4_SCHPO !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HST4_SCHPO !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HST4_SCHPO !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
RAD3_SCHPO | rad3 | genetic | 18344406 | |
RHP9_SCHPO | crb2 | genetic | 18344406 | |
MRC1_SCHPO | mrc1 | genetic | 18344406 | |
CDS1_SCHPO | cds1 | genetic | 18344406 | |
CHK1_SCHPO | chk1 | genetic | 18344406 | |
MAG1_SCHPO | mag1 | genetic | 18344406 | |
APN2_SCHPO | apn2 | genetic | 18344406 | |
FEN1_SCHPO | rad2 | genetic | 18344406 | |
RAD13_SCHPO | rad13 | genetic | 18344406 | |
RAD50_SCHPO | rad50 | genetic | 18344406 | |
YAS5_SCHPO | mms1 | genetic | 21183410 | |
AMS2_SCHPO | ams2 | genetic | 23195958 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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