HFR1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HFR1_ARATH
• UniProt AC: Q9FE22
• Protein Name: Transcription factor HFR1 {ECO:0000303|PubMed:10995393}
• Gene Name: HFR1 {ECO:0000303|PubMed:10995393}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 292
• Subcellular Localization: Nucleus .
• Protein Description: Atypical bHLH transcription factor that regulates photomorphogenesis through modulation of phytochrome (e.g. PHYA) and cryptochrome signalings (Ref.4, PubMed:11090209, PubMed:10995393, PubMed:19482971). Suppresses the transcriptional regulation activity of PIF4 by forming non-DNA-binding heterodimer..
• Protein Sequence: MSNNQAFMELGWRNDVGSLAVKDQGMMSERARSDEDRLINGLKWGYGYFDHDQTDNYLQIVPEIHKEVENAKEDLLVVVPDEHSETDDHHHIKDFSERSDHRFYLRNKHENPKKRRIQVLSSDDESEEFTREVPSVTRKGSKRRRRDEKMSNKMRKLQQLVPNCHKTDKVSVLDKTIEYMKNLQLQLQMMSTVGVNPYFLPATLGFGMHNHMLTAMASAHGLNPANHMMPSPLIPALNWPLPPFTNISFPHSSSQSLFLTTSSPASSPQSLHGLVPYFPSFLDFSSHAMRRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of HFR1_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	COP1	P43254	PMID:22199232

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HFR1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HFR1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LAF1_ARATH	MYB18	genetic	17699755
LAF1_ARATH	MYB18	physical	17699755
PIF3_ARATH	PIF3	physical	10995393
PRE6_ARATH	KDR	physical	16786307
SPA1_ARATH	SPA1	physical	15960622
COP1_ARATH	COP1	physical	15620659
CSK2B_ARATH	CKB1	physical	18556661
CSK2C_ARATH	CKB2	physical	18556661
COP1_ARATH	COP1	physical	15705947
PIF4_ARATH	PIF4	physical	19851283
PIF5_ARATH	PIL6	physical	19851283
PIF1_ARATH	PIL5	physical	21928113
PIF1_ARATH	PIL5	physical	24179122
HFR1_ARATH	HFR1	physical	24179122
HY5_ARATH	HY5	physical	23503597

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.