dbPTM

GUS_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GUS_DROME
UniProt AC	A1Z6E0
Protein Name	Protein gustavus {ECO:0000312\|EMBL:AAM68373.2}
Gene Name	gus
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	279
Subcellular Localization	Cytoplasm . Nucleus . Component of the cytoplasmic ribonucleoprotein (RNP) bodies which concentrate at the perinuclear region of the nurse cell and in punctate aggregates throughout the cytoplasm. Some cortical enrichment of these aggregates is also
Protein Description	Involved in the localization of vas to the posterior pole of the oocyte. Required maternally in the germ line for efficient primordial germ cell formation..
Protein Sequence	MGQKISGGVKTVSRNDSQSTFKPIIPRELQADFVKPARIDILLDMPPASRDLQLKHSWNSEDRSLNIFVKEDDKLTFHRHPVAQSTDCIRGKVGLTKGLHIWEIYWPTRQRGTHAVVGVCTADAPLHSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYPAILKNDEAFLVPDKFLVALDMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIVSAVWGHCEITMRYIGGLDPEPLPLMDLCRRTIRQKIGRTNLEEHIQQLQLPLSMKTYLLYKNRR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
17	Phosphorylation	KTVSRNDSQSTFKPI EEEECCCCCCCCCCC		21082442
101	Phosphorylation	GLTKGLHIWEIYWPT CCCCCEEEEEEEECC		19060867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GUS_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GUS_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GUS_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RL38_DROME	RpL38	physical	14605208
FTZF1_DROME	ftz-f1	physical	14605208
NASP_DROME	CG8223	physical	14605208
ATRIP_DROME	mus304	physical	14605208
SOX15_DROME	Sox15	physical	14605208
RS29_DROME	RpS29	physical	14605208
AFF4_DROME	lilli	physical	14605208
PPIA_DROME	Cyp1	physical	14605208
ELOB_MOUSE	Tceb2	physical	16498413
ELOC_MOUSE	Tceb1	physical	16498413
VASA2_DROME	vas	physical	16498413
VASA1_DROME	vas	physical	16498413
FBSP1_DROME	Fsn	genetic	20123973

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GUS_DROME

Related Literatures of Post-Translational Modification