| UniProt ID | GRM2B_HUMAN | |
|---|---|---|
| UniProt AC | Q96HH9 | |
| Protein Name | GRAM domain-containing protein 2B | |
| Gene Name | GRAMD2B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 432 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MTELQQDV -------CCCHHHHH | 22814378 | ||
| 13 (in isoform 4) | Phosphorylation | - | 26657352 | ||
| 26 | Phosphorylation | KRESKLGSAHSEAEN CCHHHCCCCCHHHHH | 29255136 | ||
| 29 | Phosphorylation | SKLGSAHSEAENGVE HHCCCCCHHHHHCHH | 29255136 | ||
| 44 | Phosphorylation | EKKKACRSPTAQSPT HHHHHHCCCCCCCCC | 30278072 | ||
| 46 | Phosphorylation | KKACRSPTAQSPTPS HHHHCCCCCCCCCCC | 30278072 | ||
| 49 | Phosphorylation | CRSPTAQSPTPSVEA HCCCCCCCCCCCCCC | 26657352 | ||
| 51 | Phosphorylation | SPTAQSPTPSVEADS CCCCCCCCCCCCCCC | 23663014 | ||
| 53 | Phosphorylation | TAQSPTPSVEADSPD CCCCCCCCCCCCCCC | 23663014 | ||
| 58 | Phosphorylation | TPSVEADSPDQKKII CCCCCCCCCCHHHHH | 23663014 | ||
| 71 | Phosphorylation | IISLWSKSSFDGASL HHHHHHCCCCCCCHH | 25159151 | ||
| 72 | Phosphorylation | ISLWSKSSFDGASLA HHHHHCCCCCCCHHC | 25159151 | ||
| 77 | Phosphorylation | KSSFDGASLASDKND CCCCCCCHHCCCCCC | 29396449 | ||
| 79 (in isoform 2) | Phosphorylation | - | 25159151 | ||
| 80 (in isoform 2) | Phosphorylation | - | 25159151 | ||
| 80 | Phosphorylation | FDGASLASDKNDCKT CCCCHHCCCCCCCCC | 23312004 | ||
| 91 | Ubiquitination | DCKTESKNDPKTERK CCCCCCCCCCCCCHH | 29967540 | ||
| 95 | Phosphorylation | ESKNDPKTERKKSSS CCCCCCCCCHHHCCC | 20068231 | ||
| 100 | Phosphorylation | PKTERKKSSSSSQYK CCCCHHHCCCHHHHH | 30576142 | ||
| 101 | Phosphorylation | KTERKKSSSSSQYKA CCCHHHCCCHHHHHH | 20068231 | ||
| 102 | Phosphorylation | TERKKSSSSSQYKAN CCHHHCCCHHHHHHH | 20068231 | ||
| 103 | Phosphorylation | ERKKSSSSSQYKANM CHHHCCCHHHHHHHH | 30576142 | ||
| 104 | Phosphorylation | RKKSSSSSQYKANMH HHHCCCHHHHHHHHH | 20068231 | ||
| 106 | Phosphorylation | KSSSSSQYKANMHFH HCCCHHHHHHHHHHH | 30576142 | ||
| 107 | Ubiquitination | SSSSSQYKANMHFHK CCCHHHHHHHHHHHH | 29967540 | ||
| 115 | Ubiquitination | ANMHFHKLFLSVPTE HHHHHHHHHHCCCCC | 29967540 | ||
| 118 | Phosphorylation | HFHKLFLSVPTEEPL HHHHHHHCCCCCCCC | 29978859 | ||
| 121 | Phosphorylation | KLFLSVPTEEPLKQS HHHHCCCCCCCCCHH | 29978859 | ||
| 122 | Ubiquitination | LFLSVPTEEPLKQSF HHHCCCCCCCCCHHH | 29967540 | ||
| 164 | Phosphorylation | FGKDTKISIPAFSVT HCCCCEEEEEEEEEE | 25332170 | ||
| 169 | Phosphorylation | KISIPAFSVTLIKKT EEEEEEEEEEEECCC | 25332170 | ||
| 171 | Phosphorylation | SIPAFSVTLIKKTKT EEEEEEEEEECCCCC | - | ||
| 193 | Ubiquitination | LIIATVTDRYIFVSL EEEEEECCCHHHHHH | 29967540 | ||
| 195 | Ubiquitination | IATVTDRYIFVSLLS EEEECCCHHHHHHHC | 29967540 | ||
| 195 | Phosphorylation | IATVTDRYIFVSLLS EEEECCCHHHHHHHC | 19664994 | ||
| 199 | Phosphorylation | TDRYIFVSLLSRDST CCCHHHHHHHCCHHH | 24719451 | ||
| 202 | Phosphorylation | YIFVSLLSRDSTYKL HHHHHHHCCHHHHHH | 24719451 | ||
| 205 | Phosphorylation | VSLLSRDSTYKLLKS HHHHCCHHHHHHHHH | 20068231 | ||
| 206 | Phosphorylation | SLLSRDSTYKLLKSV HHHCCHHHHHHHHHH | 20068231 | ||
| 207 | Phosphorylation | LLSRDSTYKLLKSVC HHCCHHHHHHHHHHH | 20068231 | ||
| 211 | Ubiquitination | DSTYKLLKSVCGHLE HHHHHHHHHHHCCHH | 29967540 | ||
| 212 | Phosphorylation | STYKLLKSVCGHLEN HHHHHHHHHHCCHHC | 23927012 | ||
| 219 | Ubiquitination | SVCGHLENTSVGNSP HHHCCHHCCCCCCCC | 29967540 | ||
| 220 | Phosphorylation | VCGHLENTSVGNSPN HHCCHHCCCCCCCCC | 30278072 | ||
| 221 | Phosphorylation | CGHLENTSVGNSPNP HCCHHCCCCCCCCCC | 28355574 | ||
| 225 | Phosphorylation | ENTSVGNSPNPSSAE HCCCCCCCCCCCHHC | 28355574 | ||
| 226 | Ubiquitination | NTSVGNSPNPSSAEN CCCCCCCCCCCHHCC | 29967540 | ||
| 229 | Phosphorylation | VGNSPNPSSAENSFR CCCCCCCCHHCCCCC | 23663014 | ||
| 230 | Ubiquitination | GNSPNPSSAENSFRA CCCCCCCHHCCCCCC | 29967540 | ||
| 230 | Phosphorylation | GNSPNPSSAENSFRA CCCCCCCHHCCCCCC | 23927012 | ||
| 234 | Phosphorylation | NPSSAENSFRADRPS CCCHHCCCCCCCCCC | 23663014 | ||
| 241 | Phosphorylation | SFRADRPSSLPLDFN CCCCCCCCCCCCCCC | 30266825 | ||
| 242 | Phosphorylation | FRADRPSSLPLDFND CCCCCCCCCCCCCCC | 30266825 | ||
| 252 | Phosphorylation | LDFNDEFSDLDGVVQ CCCCCCCCCCHHHHH | 30266825 | ||
| 270 | Phosphorylation | QDMEGYSSSGSQTPE HHHCCCCCCCCCCCC | 27251275 | ||
| 271 | Phosphorylation | DMEGYSSSGSQTPES HHCCCCCCCCCCCCC | 27251275 | ||
| 273 | Phosphorylation | EGYSSSGSQTPESEN CCCCCCCCCCCCCCC | 27251275 | ||
| 275 | Phosphorylation | YSSSGSQTPESENSR CCCCCCCCCCCCCCC | 30242111 | ||
| 278 | Phosphorylation | SGSQTPESENSRDFH CCCCCCCCCCCCCEE | 27251275 | ||
| 281 | Ubiquitination | QTPESENSRDFHATE CCCCCCCCCCEEECC | 29967540 | ||
| 287 | Phosphorylation | NSRDFHATESQTVLN CCCCEEECCEEEEEE | 28857561 | ||
| 289 | Phosphorylation | RDFHATESQTVLNVS CCEEECCEEEEEEEC | 28857561 | ||
| 291 | Phosphorylation | FHATESQTVLNVSKG EEECCEEEEEEECCC | 28857561 | ||
| 296 | Phosphorylation | SQTVLNVSKGEAKPT EEEEEEECCCCCCCC | 20068231 | ||
| 297 | Ubiquitination | QTVLNVSKGEAKPTR EEEEEECCCCCCCCC | 29967540 | ||
| 305 | Ubiquitination | GEAKPTRADAHVNRV CCCCCCCCCCCCCCC | 29967540 | ||
| 312 | Ubiquitination | ADAHVNRVPEGKAKS CCCCCCCCCCCCCCC | 29967540 | ||
| 318 | Ubiquitination | RVPEGKAKSLPVQGL CCCCCCCCCCCCCCH | 29967540 | ||
| 319 | Phosphorylation | VPEGKAKSLPVQGLS CCCCCCCCCCCCCHH | 23898821 | ||
| 326 | Phosphorylation | SLPVQGLSETVGILH CCCCCCHHHHHHHHH | 18452278 | ||
| 334 | Ubiquitination | ETVGILHKVKSQKCP HHHHHHHHHHHCCCC | 29967540 | ||
| 342 | Ubiquitination | VKSQKCPMLHHILIF HHHCCCCHHHHHHHH | 29967540 | ||
| 349 | Ubiquitination | MLHHILIFYAIVVCA HHHHHHHHHHHHHHH | 29967540 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GRM2B_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GRM2B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GRM2B_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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