UniProt ID | GRM2B_HUMAN | |
---|---|---|
UniProt AC | Q96HH9 | |
Protein Name | GRAM domain-containing protein 2B | |
Gene Name | GRAMD2B | |
Organism | Homo sapiens (Human). | |
Sequence Length | 432 | |
Subcellular Localization | ||
Protein Description | ||
Protein Sequence | MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
1 | Acetylation | -------MTELQQDV -------CCCHHHHH | 22814378 | ||
13 (in isoform 4) | Phosphorylation | - | 26657352 | ||
26 | Phosphorylation | KRESKLGSAHSEAEN CCHHHCCCCCHHHHH | 29255136 | ||
29 | Phosphorylation | SKLGSAHSEAENGVE HHCCCCCHHHHHCHH | 29255136 | ||
44 | Phosphorylation | EKKKACRSPTAQSPT HHHHHHCCCCCCCCC | 30278072 | ||
46 | Phosphorylation | KKACRSPTAQSPTPS HHHHCCCCCCCCCCC | 30278072 | ||
49 | Phosphorylation | CRSPTAQSPTPSVEA HCCCCCCCCCCCCCC | 26657352 | ||
51 | Phosphorylation | SPTAQSPTPSVEADS CCCCCCCCCCCCCCC | 23663014 | ||
53 | Phosphorylation | TAQSPTPSVEADSPD CCCCCCCCCCCCCCC | 23663014 | ||
58 | Phosphorylation | TPSVEADSPDQKKII CCCCCCCCCCHHHHH | 23663014 | ||
71 | Phosphorylation | IISLWSKSSFDGASL HHHHHHCCCCCCCHH | 25159151 | ||
72 | Phosphorylation | ISLWSKSSFDGASLA HHHHHCCCCCCCHHC | 25159151 | ||
77 | Phosphorylation | KSSFDGASLASDKND CCCCCCCHHCCCCCC | 29396449 | ||
79 (in isoform 2) | Phosphorylation | - | 25159151 | ||
80 (in isoform 2) | Phosphorylation | - | 25159151 | ||
80 | Phosphorylation | FDGASLASDKNDCKT CCCCHHCCCCCCCCC | 23312004 | ||
91 | Ubiquitination | DCKTESKNDPKTERK CCCCCCCCCCCCCHH | 29967540 | ||
95 | Phosphorylation | ESKNDPKTERKKSSS CCCCCCCCCHHHCCC | 20068231 | ||
100 | Phosphorylation | PKTERKKSSSSSQYK CCCCHHHCCCHHHHH | 30576142 | ||
101 | Phosphorylation | KTERKKSSSSSQYKA CCCHHHCCCHHHHHH | 20068231 | ||
102 | Phosphorylation | TERKKSSSSSQYKAN CCHHHCCCHHHHHHH | 20068231 | ||
103 | Phosphorylation | ERKKSSSSSQYKANM CHHHCCCHHHHHHHH | 30576142 | ||
104 | Phosphorylation | RKKSSSSSQYKANMH HHHCCCHHHHHHHHH | 20068231 | ||
106 | Phosphorylation | KSSSSSQYKANMHFH HCCCHHHHHHHHHHH | 30576142 | ||
107 | Ubiquitination | SSSSSQYKANMHFHK CCCHHHHHHHHHHHH | 29967540 | ||
115 | Ubiquitination | ANMHFHKLFLSVPTE HHHHHHHHHHCCCCC | 29967540 | ||
118 | Phosphorylation | HFHKLFLSVPTEEPL HHHHHHHCCCCCCCC | 29978859 | ||
121 | Phosphorylation | KLFLSVPTEEPLKQS HHHHCCCCCCCCCHH | 29978859 | ||
122 | Ubiquitination | LFLSVPTEEPLKQSF HHHCCCCCCCCCHHH | 29967540 | ||
164 | Phosphorylation | FGKDTKISIPAFSVT HCCCCEEEEEEEEEE | 25332170 | ||
169 | Phosphorylation | KISIPAFSVTLIKKT EEEEEEEEEEEECCC | 25332170 | ||
171 | Phosphorylation | SIPAFSVTLIKKTKT EEEEEEEEEECCCCC | - | ||
193 | Ubiquitination | LIIATVTDRYIFVSL EEEEEECCCHHHHHH | 29967540 | ||
195 | Ubiquitination | IATVTDRYIFVSLLS EEEECCCHHHHHHHC | 29967540 | ||
195 | Phosphorylation | IATVTDRYIFVSLLS EEEECCCHHHHHHHC | 19664994 | ||
199 | Phosphorylation | TDRYIFVSLLSRDST CCCHHHHHHHCCHHH | 24719451 | ||
202 | Phosphorylation | YIFVSLLSRDSTYKL HHHHHHHCCHHHHHH | 24719451 | ||
205 | Phosphorylation | VSLLSRDSTYKLLKS HHHHCCHHHHHHHHH | 20068231 | ||
206 | Phosphorylation | SLLSRDSTYKLLKSV HHHCCHHHHHHHHHH | 20068231 | ||
207 | Phosphorylation | LLSRDSTYKLLKSVC HHCCHHHHHHHHHHH | 20068231 | ||
211 | Ubiquitination | DSTYKLLKSVCGHLE HHHHHHHHHHHCCHH | 29967540 | ||
212 | Phosphorylation | STYKLLKSVCGHLEN HHHHHHHHHHCCHHC | 23927012 | ||
219 | Ubiquitination | SVCGHLENTSVGNSP HHHCCHHCCCCCCCC | 29967540 | ||
220 | Phosphorylation | VCGHLENTSVGNSPN HHCCHHCCCCCCCCC | 30278072 | ||
221 | Phosphorylation | CGHLENTSVGNSPNP HCCHHCCCCCCCCCC | 28355574 | ||
225 | Phosphorylation | ENTSVGNSPNPSSAE HCCCCCCCCCCCHHC | 28355574 | ||
226 | Ubiquitination | NTSVGNSPNPSSAEN CCCCCCCCCCCHHCC | 29967540 | ||
229 | Phosphorylation | VGNSPNPSSAENSFR CCCCCCCCHHCCCCC | 23663014 | ||
230 | Ubiquitination | GNSPNPSSAENSFRA CCCCCCCHHCCCCCC | 29967540 | ||
230 | Phosphorylation | GNSPNPSSAENSFRA CCCCCCCHHCCCCCC | 23927012 | ||
234 | Phosphorylation | NPSSAENSFRADRPS CCCHHCCCCCCCCCC | 23663014 | ||
241 | Phosphorylation | SFRADRPSSLPLDFN CCCCCCCCCCCCCCC | 30266825 | ||
242 | Phosphorylation | FRADRPSSLPLDFND CCCCCCCCCCCCCCC | 30266825 | ||
252 | Phosphorylation | LDFNDEFSDLDGVVQ CCCCCCCCCCHHHHH | 30266825 | ||
270 | Phosphorylation | QDMEGYSSSGSQTPE HHHCCCCCCCCCCCC | 27251275 | ||
271 | Phosphorylation | DMEGYSSSGSQTPES HHCCCCCCCCCCCCC | 27251275 | ||
273 | Phosphorylation | EGYSSSGSQTPESEN CCCCCCCCCCCCCCC | 27251275 | ||
275 | Phosphorylation | YSSSGSQTPESENSR CCCCCCCCCCCCCCC | 30242111 | ||
278 | Phosphorylation | SGSQTPESENSRDFH CCCCCCCCCCCCCEE | 27251275 | ||
281 | Ubiquitination | QTPESENSRDFHATE CCCCCCCCCCEEECC | 29967540 | ||
287 | Phosphorylation | NSRDFHATESQTVLN CCCCEEECCEEEEEE | 28857561 | ||
289 | Phosphorylation | RDFHATESQTVLNVS CCEEECCEEEEEEEC | 28857561 | ||
291 | Phosphorylation | FHATESQTVLNVSKG EEECCEEEEEEECCC | 28857561 | ||
296 | Phosphorylation | SQTVLNVSKGEAKPT EEEEEEECCCCCCCC | 20068231 | ||
297 | Ubiquitination | QTVLNVSKGEAKPTR EEEEEECCCCCCCCC | 29967540 | ||
305 | Ubiquitination | GEAKPTRADAHVNRV CCCCCCCCCCCCCCC | 29967540 | ||
312 | Ubiquitination | ADAHVNRVPEGKAKS CCCCCCCCCCCCCCC | 29967540 | ||
318 | Ubiquitination | RVPEGKAKSLPVQGL CCCCCCCCCCCCCCH | 29967540 | ||
319 | Phosphorylation | VPEGKAKSLPVQGLS CCCCCCCCCCCCCHH | 23898821 | ||
326 | Phosphorylation | SLPVQGLSETVGILH CCCCCCHHHHHHHHH | 18452278 | ||
334 | Ubiquitination | ETVGILHKVKSQKCP HHHHHHHHHHHCCCC | 29967540 | ||
342 | Ubiquitination | VKSQKCPMLHHILIF HHHCCCCHHHHHHHH | 29967540 | ||
349 | Ubiquitination | MLHHILIFYAIVVCA HHHHHHHHHHHHHHH | 29967540 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GRM2B_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GRM2B_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GRM2B_HUMAN !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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