EFC14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EFC14_HUMAN
• UniProt AC: O75071
• Protein Name: EF-hand calcium-binding domain-containing protein 14
• Gene Name: EFCAB14
• Organism: Homo sapiens (Human).
• Sequence Length: 495
• Protein Sequence: MKKRKELNALIGLAGDSRRKKPKKGPSSHRLLRTEPPDSDSESSSEEEEEFGVVGNRSRFAKGDYLRCCKICYPLCGFVILAACVVACVGLVWMQVALKEDLDALKEKFRTMESNQKSSFQEIPKLNEELLSKQKQLEKIESGEMGLNKVWINITEMNKQISLLTSAVNHLKANVKSAADLISLPTTVEGLQKSVASIGNTLNSVHLAVEALQKTVDEHKKTMELLQSDMNQHFLKETPGSNQIIPSPSATSELDNKTHSENLKQDILYLHNSLEEVNSALVGYQRQNDLKLEGMNETVSNLTQRVNLIESDVVAMSKVEKKANLSFSMMGDRSATLKRQSLDQVTNRTDTVKIQSIKKEDSSNSQVSKLREKLQLISALTNKPESNRPPETADEEQVESFTSKPSALPKFSQFLGDPVEKAAQLRPISLPGVSSTEDLQDLFRKTGQDVDGKLTYQEIWTSLGSAMPEPESLRAFDSDGDGRYSFLELRVALGI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	LIGLAGDSRRKKPKK HHHHCCCCCCCCCCC		25787250
111	Phosphorylation	ALKEKFRTMESNQKS HHHHHHHHHHHHCCC		27251275
114	Phosphorylation	EKFRTMESNQKSSFQ HHHHHHHHHCCCCHH		27251275
118	Phosphorylation	TMESNQKSSFQEIPK HHHHHCCCCHHHCHH		27251275
119	Phosphorylation	MESNQKSSFQEIPKL HHHHCCCCHHHCHHH		27251275
142	Phosphorylation	KQLEKIESGEMGLNK HHHHHHHHCCCCCCE		-
162	Phosphorylation	TEMNKQISLLTSAVN HHHHHHHHHHHHHHH		23403867
166	Phosphorylation	KQISLLTSAVNHLKA HHHHHHHHHHHHHHH		23403867
186	O-linked_Glycosylation	ADLISLPTTVEGLQK HHHHCCCCHHHHHHH		OGP
247	O-linked_Glycosylation	GSNQIIPSPSATSEL CCCCCCCCCCCCCCC		OGP
249	Phosphorylation	NQIIPSPSATSELDN CCCCCCCCCCCCCCC		30576142
252	Phosphorylation	IPSPSATSELDNKTH CCCCCCCCCCCCCCC		30576142
326	Phosphorylation	VEKKANLSFSMMGDR HCHHHCCCHHHCCCH		-
328	Phosphorylation	KKANLSFSMMGDRSA HHHCCCHHHCCCHHH		25002506
334	Phosphorylation	FSMMGDRSATLKRQS HHHCCCHHHHHHHHC		25002506
336	Phosphorylation	MMGDRSATLKRQSLD HCCCHHHHHHHHCHH		25002506
341	Phosphorylation	SATLKRQSLDQVTNR HHHHHHHCHHHHHCC		27174698
346	Phosphorylation	RQSLDQVTNRTDTVK HHCHHHHHCCCCCEE		27174698
349	Phosphorylation	LDQVTNRTDTVKIQS HHHHHCCCCCEEEEC		27174698
351	Phosphorylation	QVTNRTDTVKIQSIK HHHCCCCCEEEECCC		27174698
356	Phosphorylation	TDTVKIQSIKKEDSS CCCEEEECCCCCCCC		27174698
362	Phosphorylation	QSIKKEDSSNSQVSK ECCCCCCCCCHHHHH		29978859
363	Phosphorylation	SIKKEDSSNSQVSKL CCCCCCCCCHHHHHH		29978859
365	Phosphorylation	KKEDSSNSQVSKLRE CCCCCCCHHHHHHHH		29978859
368	Phosphorylation	DSSNSQVSKLREKLQ CCCCHHHHHHHHHHH		29978859
369	Acetylation	SSNSQVSKLREKLQL CCCHHHHHHHHHHHH		19811461
386	Phosphorylation	ALTNKPESNRPPETA HHHCCCHHCCCCCCC		22468782
392	Phosphorylation	ESNRPPETADEEQVE HHCCCCCCCCHHHHH		22468782
402	O-linked_Glycosylation	EEQVESFTSKPSALP HHHHHHHHCCCCCCH		OGP
406	Phosphorylation	ESFTSKPSALPKFSQ HHHHCCCCCCHHHHH		17192257
412	O-linked_Glycosylation	PSALPKFSQFLGDPV CCCCHHHHHHHCCHH		55825627
434	Phosphorylation	PISLPGVSSTEDLQD CCCCCCCCCHHHHHH		28348404
435	Phosphorylation	ISLPGVSSTEDLQDL CCCCCCCCHHHHHHH		28857561
436	Phosphorylation	SLPGVSSTEDLQDLF CCCCCCCHHHHHHHH		28348404
465	O-linked_Glycosylation	EIWTSLGSAMPEPES HHHHHHCCCCCCCHH		OGP
485	Phosphorylation	SDGDGRYSFLELRVA CCCCCCEEEEEHHHH		27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EFC14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EFC14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EFC14_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of EFC14_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.