dbPTM

FIG4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FIG4_SCHPO
UniProt AC	Q7Z9H9
Protein Name	Polyphosphoinositide phosphatase
Gene Name	SPAC1093.03
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	832
Subcellular Localization	Cytoplasm . Vacuole membrane Peripheral membrane protein.
Protein Description	The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)..
Protein Sequence	MPATNSDEPLVKFELYQLKKCYYIVSENATATIFRILKITQSEDELSISIEEAAKILFRQKLQLYLEKLENESADGKLILVTKAYAILGLFRFTAGYYLYLCTERKVVAVIGGHNVYHVDKTQFIELNPSRRHNTSVERKCMSSIEKVDLARTFYFSYSYDLSQTIQYGFTHPIPQHQVRDMFVWNWNMLRPILDSVGIDSPWCIPLIHGFVDQAKLSVYGKPIIVTLIARRSRHFAGARFLRRGIRDDGYVANEVETEQIVFDGSASSFPISSTTPGIPCYTSYVQHRGSIPLRWSQEFSNITPKPPIGIDFHDPFYASTALHFDRLFGHYGIPCIVLNLVKSSEKVKRESLLLDEFESAIQYLNQFLKDSQKIQYIAWDMSAASKKKVPVTKTLEQMASDIVKKTGFFCTADRFFPGTFQTGVVRTNCVDCLDRTNAAQFVIGKCVLAAQLRALGVLDSPQLDYESDAVRLLAEMYHGHGDAIALQYGGSLLVNTLDTYRKNNQWSSTSRDLIESVKRFYSNSFVDFQRQEAISLFLGNFTVHGKIVVFGEKRLQALTEKFKNGQLVRRDYRYWWTPVYVNQELRCKNAYCDSIQRKGIKFPANYFDNVYTPNSISSFSEVLLPNLISTLNFAPLSLIPLLRKSFLPLSYNGFGIEAPSLNPFIPRRNQPRDMFKTSAEEENEDEDEDDDKFRRVSLYKWLFNNEERPVHKFIRKRLHQIPVSNKVQPRDQKQPDFKIPNTDINVYKIHFQYNNISGLADNYTLLSKHDRAMYNNYADYSPDKIKEIKEKELNTYNDYFNSAISENPTLKSDRSEKVAFYSAWITDYKST

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of FIG4_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FIG4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FIG4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FIG4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DBR1_SCHPO	dbr1	genetic	18818364
YJ03_SCHPO	rhn1	genetic	18818364
FUB1_SCHPO	SPAC15E1.10	genetic	18818364
HRP1_SCHPO	hrp1	genetic	18818364
YF2C_SCHPO	rrp1	genetic	18818364
RAD25_SCHPO	rad25	genetic	18818364
HOP2_SCHPO	meu13	genetic	18818364
DSK2_SCHPO	dph1	genetic	18818364
POM1_SCHPO	pom1	genetic	18818364
MED1_SCHPO	pmc2	genetic	18818364
ATP11_SCHPO	atp11	genetic	18818364
ABP1_SCHPO	cbp1	genetic	18818364
REB1_SCHPO	reb1	genetic	18818364
DENR_SCHPO	SPBC16C6.05	genetic	18818364
MLH1_SCHPO	mlh1	genetic	18818364
ASK1_SCHPO	ask1	genetic	18818364
NGG1_SCHPO	ngg1	genetic	18818364
MUB1_SCHPO	SPBC31F10.10c	genetic	18818364
TMA20_SCHPO	tma20	genetic	18818364
SERB_SCHPO	ser2	genetic	18818364
ELP6_SCHPO	elp6	genetic	18818364
SNF8_SCHPO	dot2	genetic	18818364
UBP3_SCHPO	ubp3	genetic	18818364
AAKB_SCHPO	amk2	genetic	18818364
VPH2_SCHPO	vph2	genetic	18818364
YG58_SCHPO	SPBC56F2.08c	genetic	22681890
MU115_SCHPO	mug115	genetic	22681890
YFQ6_SCHPO	SPAC8E11.06	genetic	22681890
CDA1_SCHPO	cda1	genetic	22681890
YQJ9_SCHPO	SPCC1840.09	genetic	22681890
MGR2_SCHPO	mgr2	genetic	22681890
YE08_SCHPO	SPAC17H9.08	genetic	22681890
PPR2_SCHPO	ppr2	genetic	22681890
YBPC_SCHPO	SPBC16H5.12c	genetic	22681890
PFF1_SCHPO	SPCC1919.12c	genetic	22681890
BTB1_SCHPO	btb1	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FIG4_SCHPO

Related Literatures of Post-Translational Modification