dbPTM

PFF1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PFF1_SCHPO
UniProt AC	O94479
Protein Name	Vacuolar membrane protease {ECO:0000250\|UniProtKB:P38244}
Gene Name	SPCC1919.12c {ECO:0000312\|PomBase:SPCC1919.12c}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	843
Subcellular Localization	Membrane . Vacuole membrane Multi-pass membrane protein .
Protein Description	May be involved in vacuolar sorting and osmoregulation..
Protein Sequence	MTNSRRHIFERICAKAFQSSLTCSIFGFTVLLILYLLDWKRIAQVPGPNLLKDLEFQRAWNDLEYISSLPHPYNSKQNEHVRSYILKSMRELEATNQSYITVIDDTLTNITFESTDNDTLTYFEGDNILVKFEGKSKDLFPILLSAHFDSVSTGYGATDDGMGVATVMAIARYYAKNQPNRDLIININNAEEDYLFGAKAFASHKLSKNVTAFVNLEGAGSGGKAMLFRSSNGHVSSAYFKGNHYPLASILGNDFFKRGVIRSQTDYIVYEKMHNHTAGLDIAFYENRDIYHTRKDDINHLMPSSLRHMMYTASNAVKNLLNDSKSDLTKFRKPMFFLAFGKYWQLNLPIYQVLNIIFAVICPIVLLLTLIRFPSLYEQLKKPRYTVCFVVSCIFVSIFDTLTVLLLTWINPYVINSHTGLILALFYLTNLIALAFSFRAAATHSKLSSEDLSSIEIVFIWYAQILWYLVFIVSVILSIYFQLGSTYWVTLSYLCTFTCCIMTIIRINYFVDNVVTTQTTHEEDALIGSSINTSSHQHYGSTLNSTPHRRNSIALSNRAHVKLIDNIWTVIYFIFNVPFPVFLCYDILVETILPAGSQTLTDSVFSSKLYKLVIFVVFLSLVNSGPFIFRALSKKSLAVLTMLWITLFVQALSVNPFTESAPLKLSFVQMYDMDRMNNTVYVKNISPFTQDVLSLNPHFLFSNGSCNTSLCYYESTDPDFGGLKTPMSIHIEREKHQLDISINSGSKWCYVDFNTSVFFEAINGNSISGMYSSVRMGQRSFYAPYTLNLTITEVVKAEVTCLYDDIHEGIIPAYNTFVEHLPSWVAGVKASTGLLKVKSSIVI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
96	N-linked_Glycosylation	MRELEATNQSYITVI HHHHHHHCCCEEEEE	-
109	N-linked_Glycosylation	VIDDTLTNITFESTD EEECCCEEEEEECCC	-
117	N-linked_Glycosylation	ITFESTDNDTLTYFE EEEECCCCCEEEEEE	-
209	N-linked_Glycosylation	ASHKLSKNVTAFVNL HCCCCCCCEEEEEEE	-
275	N-linked_Glycosylation	IVYEKMHNHTAGLDI EEEECCCCCCCCCEE	-
322	N-linked_Glycosylation	NAVKNLLNDSKSDLT HHHHHHHHCCHHHHH	-
552	Phosphorylation	STPHRRNSIALSNRA CCCCCCCCCHHCCHH	28889911
677	N-linked_Glycosylation	MYDMDRMNNTVYVKN EEEHHCCCCEEEEEE	-
703	N-linked_Glycosylation	NPHFLFSNGSCNTSL CCCEEECCCCCCCEE	-
707	N-linked_Glycosylation	LFSNGSCNTSLCYYE EECCCCCCCEEEEEE	-
754	N-linked_Glycosylation	KWCYVDFNTSVFFEA CEEEEECCCEEEEEE	-
788	N-linked_Glycosylation	FYAPYTLNLTITEVV EECCEEEEEEEHHHH	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PFF1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PFF1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PFF1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PFF1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PFF1_SCHPO

Related Literatures of Post-Translational Modification