FAXC_DROME - dbPTM
FAXC_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FAXC_DROME
UniProt AC Q95RI5
Protein Name Failed axon connections
Gene Name fax
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 418
Subcellular Localization
Protein Description Together with Abl, involved in embryonic axonal development..
Protein Sequence MASEVAQIPAEETPAVAAAEKSEEPEKSAAPPADSAAAPAAAPAVEKAEDADGEKKDGEAGKQDKQQDGEEPKKDEAVAAPVATKSEAPPAQKFNVHKTNFEKDIIYLYQFSRTPLLPSLSPYCLKVETWLRLVGLKYENVDHKMRFRSKKGQLPFIELNGEEIADSAIIIKELSSKYEKYLDSGLTAEQRNVSYATIAMLENHLIWIIFYWRAKYPDNVLKGYKVNLQHALGLRLPNSILNFFFKITFGRKWFQGTKKLKAHGIGVHSAEEIEEFGKDDLKVLSEMLDCKPFFFGDEPTTLDVVAFAVLSQLHYLSKDIAYPLRDYMTEKCPNLIGHVSRMKDKCFPDWDEICTKLDLNAHIPKPEPETKEGKEGGEQEKSNEQEGTEGDKIEKELEKDKSNEKESTEENKEKEETK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MASEVAQIPA
-----CCCCCCCCCH
31.1627794539
22PhosphorylationAVAAAEKSEEPEKSA
HCHHHHCCCCCHHHC
38.4023607784
269PhosphorylationAHGIGVHSAEEIEEF
HCCCCCCCHHHHHHH
34.6622668510
382PhosphorylationEGGEQEKSNEQEGTE
CCCCCCCCCCCCCCH
44.8619429919
402PhosphorylationKELEKDKSNEKESTE
HHHHHCCCCCHHCHH
61.4222817900
407PhosphorylationDKSNEKESTEENKEK
CCCCCHHCHHHHHHH
52.7927794539
408PhosphorylationKSNEKESTEENKEKE
CCCCHHCHHHHHHHH
48.7027794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FAXC_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FAXC_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FAXC_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
OST48_DROMEOst48physical
22036573
EF1D_DROMEeEF1deltaphysical
22036573
YC17_DROMECG16817physical
22036573
NACA_DROMENacalphaphysical
22036573
IDH3A_DROMEl(1)G0156physical
22036573
TERA_DROMETER94physical
22036573
NLP_DROMENlpphysical
22036573
ACADM_DROMECG12262physical
22036573
SURF4_DROMESurf4physical
22036573
INO1_DROMEInosphysical
22036573
RS27A_DROMERpS27Aphysical
24292889

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FAXC_DROME

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Related Literatures of Post-Translational Modification

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