dbPTM

ELAV_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ELAV_DROME
UniProt AC	P16914
Protein Name	Protein elav
Gene Name	elav
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	483
Subcellular Localization
Protein Description	Required for the proper development and maintenance of neurons presumably by affecting RNA metabolism..
Protein Sequence	MDFIMANTGAGGGVDTQAQLMQSAAAAAAVAATNAAAAPVQNAAAVAAAAQLQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVVAQQAVVQQQQQQAAAVVQQAAVQQAVVPQPQQAQPNTNGNAGSGSQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEAIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
332	Phosphorylation	KFSNTPGSTSKIIQP EEECCCCCCCCCCCC	30.61	27794539
334	Phosphorylation	SNTPGSTSKIIQPQL ECCCCCCCCCCCCCC	24.45	27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ELAV_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ELAV_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ELAV_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ELAV_DROME	elav	physical	14605208
EWG_DROME	ewg	genetic	18419806
SLIT_DROME	sli	genetic	17049509
COMM_DROME	comm	genetic	17049509
SXL_DROME	Sxl	genetic	26124284
EWG_DROME	ewg	physical	21705751
EWG_DROME	ewg	physical	23019123
EWG_DROME	ewg	physical	24803653
ELAV_DROME	elav	physical	23019123
NRG_DROME	Nrg	physical	23019123
BRAT_DROME	brat	physical	23019123
PUM_DROME	pum	physical	23019123
FAS1_DROME	Fas1	physical	23019123
UBX_DROME	Ubx	physical	24803653

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ELAV_DROME

Related Literatures of Post-Translational Modification