DCNL4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DCNL4_HUMAN
• UniProt AC: Q92564
• Protein Name: DCN1-like protein 4
• Gene Name: DCUN1D4
• Organism: Homo sapiens (Human).
• Sequence Length: 292
• Protein Sequence: MHSDAAAVNFQLNSHLSTLANIHKIYHTLNKLNLTEDIGQDDHQTGSLRSCSSSDCFNKVMPPRKKRRPASGDDLSAKKSRHDSMYRKYDSTRIKTEEEAFSSKRCLEWFYEYAGTDDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWPLFPVFHQFLEQSKYKVINKDQWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKDKQMS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	Phosphorylation	TGSLRSCSSSDCFNK CCCCCCCCCCHHHHC	33.84	24719451
53	Phosphorylation	GSLRSCSSSDCFNKV CCCCCCCCCHHHHCC	34.23	27251275
71	Phosphorylation	RKKRRPASGDDLSAK CCCCCCCCCCCCHHH	45.50	29255136
76	Phosphorylation	PASGDDLSAKKSRHD CCCCCCCHHHHHHCH	45.07	23403867
80	Phosphorylation	DDLSAKKSRHDSMYR CCCHHHHHHCHHHHH	33.85	22210691
89	Phosphorylation	HDSMYRKYDSTRIKT CHHHHHHCCCCCCCC	13.21	30576142
91	Phosphorylation	SMYRKYDSTRIKTEE HHHHHCCCCCCCCHH	19.25	30576142
95	Sumoylation	KYDSTRIKTEEEAFS HCCCCCCCCHHHHHC	46.74	-
95	Sumoylation	KYDSTRIKTEEEAFS HCCCCCCCCHHHHHC	46.74	28112733
96	Phosphorylation	YDSTRIKTEEEAFSS CCCCCCCCHHHHHCC	46.38	23828894
102	Phosphorylation	KTEEEAFSSKRCLEW CCHHHHHCCHHHHHH	41.83	30576142
103	Phosphorylation	TEEEAFSSKRCLEWF CHHHHHCCHHHHHHH	20.05	23828894
104	Ubiquitination	EEEAFSSKRCLEWFY HHHHHCCHHHHHHHH	46.03	-
194	Ubiquitination	LNDSTNFKLIYRYAF HCCCCCHHHHHHHHH	35.72	-
238	Ubiquitination	LFPVFHQFLEQSKYK HHHHHHHHHHHHCCE	6.43	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DCNL4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DCNL4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DCNL4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CUL1_HUMAN	CUL1	physical	23201271
CUL2_HUMAN	CUL2	physical	23201271
CUL3_HUMAN	CUL3	physical	23201271
CUL4A_HUMAN	CUL4A	physical	23201271
CUL4B_HUMAN	CUL4B	physical	23201271
CUL5_HUMAN	CUL5	physical	23201271
TOP3A_HUMAN	TOP3A	physical	26344197
CUL1_HUMAN	CUL1	physical	26906416
CUL2_HUMAN	CUL2	physical	26906416
CUL3_HUMAN	CUL3	physical	26906416
CUL5_HUMAN	CUL5	physical	26906416
CAND1_HUMAN	CAND1	physical	26906416
RBX1_HUMAN	RBX1	physical	26906416
RBX2_HUMAN	RNF7	physical	26906416
UBC12_HUMAN	UBE2M	physical	26906416
ARL4C_HUMAN	ARL4C	physical	28514442
MSRB3_HUMAN	MSRB3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.