| UniProt ID | CIPKB_ARATH | |
|---|---|---|
| UniProt AC | O22932 | |
| Protein Name | CBL-interacting serine/threonine-protein kinase 11 | |
| Gene Name | CIPK11 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 435 | |
| Subcellular Localization | ||
| Protein Description | CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Acts as a negative regulator of the plasma membrane proton pump AHA2 by preventing its interaction with 14-3-3 protein.. | |
| Protein Sequence | MPEIEIAAGSGDNNDALFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRITIDEILKDPWFVRGGFKQIKFHDDEIEDQKVESSLEAVKSLNAFDLISYSSGLDLSGLFAGCSNSSGESERFLSEKSPEMLAEEVEGFAREENLRMKKKKEEEYGFEMEGQNGKFGIGICISRLNDLLVVVEARRRGGDGDCYKEMWNGKLRVQLIRVCDQTSSTNAAI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 72 | Phosphorylation | NNIKREISIMRRLSH HHHHHHHHHHHHCCC | 12.94 | 30407730 | |
| 167 | Phosphorylation | KVSDFGLSALTDQIR EECCCCHHHHCCCCC | 22.93 | - | |
| 181 | Phosphorylation | RPDGLLHTLCGTPAY CCCCHHHHHCCCCCC | 24.58 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CIPKB_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CIPKB_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CIPKB_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CNBL2_ARATH | CBL2 | physical | 17483306 | |
| PMA2_ARATH | HA2 | physical | 17483306 | |
| DNAJ3_ARATH | ATJ3 | physical | 20418496 | |
| CNBL2_ARATH | CBL2 | physical | 21685179 | |
| CNBL2_ARATH | CBL2 | physical | 21798944 | |
| CNBL9_ARATH | CBL9 | physical | 21798944 | |
| CIPKB_ARATH | SIP4 | physical | 24823379 | |
| CIPKE_ARATH | SR1 | physical | 24823379 | |
| RVE2_ARATH | RVE2 | physical | 24823379 | |
| NPR1_ARATH | NPR1 | physical | 20621018 | |
| CNBL2_ARATH | CBL2 | physical | 20621018 | |
| CNBL2_ARATH | CBL2 | physical | 24521877 | |
| CNBL3_ARATH | CBL3 | physical | 24521877 | |
| CNBLA_ARATH | CBL10 | physical | 24521877 | |
| CNBL7_ORYSJ | Os02g0291000 | physical | 24970010 | |
| CNBL4_ORYSJ | Os05g0534400 | physical | 24970010 | |
| ABI5_ARATH | ABI5 | physical | 25858916 | |
| ABI5_ARATH | ABI5 | genetic | 25858916 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
