dbPTM

C1QL4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	C1QL4_HUMAN
UniProt AC	Q86Z23
Protein Name	Complement C1q-like protein 4
Gene Name	C1QL4
Organism	Homo sapiens (Human).
Sequence Length	238
Subcellular Localization	Secreted.
Protein Description	May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity)..
Protein Sequence	MVLLLLVAIPLLVHSSRGPAHYEMLGRCRMVCDPHGPRGPGPDGAPASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPGPGGVAPAAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGGNTNKYSTFSGFIIYPD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	AIPLLVHSSRGPAHY HHHHHHHCCCCHHHH	17.79	-
16	Phosphorylation	IPLLVHSSRGPAHYE HHHHHHCCCCHHHHH	26.78	-
226	Ubiquitination	VHGGNTNKYSTFSGF EECCCCCCCCCEEEE	38.24	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of C1QL4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of C1QL4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of C1QL4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DUS3L_HUMAN	DUS3L	physical	28514442
KLH11_HUMAN	KLHL11	physical	28514442
SRC_HUMAN	SRC	physical	28514442
VHL_HUMAN	VHL	physical	28514442
PON2_HUMAN	PON2	physical	28514442
COEA1_HUMAN	COL14A1	physical	28514442
CARME_HUMAN	C9orf41	physical	28514442
BT2A2_HUMAN	BTN2A2	physical	28514442
OCC1_HUMAN	C12orf75	physical	28514442
GBG10_HUMAN	GNG10	physical	28514442
PHAG1_HUMAN	PAG1	physical	28514442
2A5E_HUMAN	PPP2R5E	physical	28514442
RASH_HUMAN	HRAS	physical	28514442
GBG5_HUMAN	GNG5	physical	28514442
COIA1_HUMAN	COL18A1	physical	28514442
YES_HUMAN	YES1	physical	28514442
SMC2_HUMAN	SMC2	physical	28514442
CSTF3_HUMAN	CSTF3	physical	28514442
GNAQ_HUMAN	GNAQ	physical	28514442
AHNK2_HUMAN	AHNAK2	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of C1QL4_HUMAN

Related Literatures of Post-Translational Modification